FasterDB - Main

		Gene
Symbol		VOPP1
Synonyms		DKFZp564K0822, ECop, FLJ20532, GASP
Description		vesicular, overexpressed in cancer, prosurvival protein 1
EnsEMBL link		ENSG00000154978
Chromosome		7 - reverse strand
Chromosomal location (UCSC link)		55538307 - 55640200 (101894bp)
Sequence		sequence
Associated transcripts		NM_030796 AK225755 XM_001723367 AK075391 AK314338 BC016650 AB097004 AL136610 XM_001129280 CR533483 AK090825 AK309288 AK315882 AK092992 AF395824

		Alternative 3' splice site (acceptor)
Identifier	Position	Distance (bp)	Transcript

		Alternative 5' splice sites (donor)
Identifier	Position	Distance (bp)	Transcript

	Intron retentions
Identifier	Position	Transcript

	Exon deletions
Identifier	Position	Transcript
No data

	Transcription start sites
Identifier	Position	Gene coordinates	Chromosomal coordinates	Transcript
P1	1	1	55640200	NM_030796
P2	1	95	55640106	AK314338
P3	2	640	55639561	AK090825
P4	3	19735	55620466	AK309288
P5	4	33848	55606353	AK315882
P6	5	34814	55605387	AK092992
P7	6	51364	55588837	AF395824

Protein prediction
Transcript name	Sequence
NM_030796	sequence
AK225755	sequence
XM_001723367	sequence
AK075391	sequence
AK314338	sequence
BC016650	sequence
AB097004	sequence
AL136610	sequence
XM_001129280	sequence
CR533483	sequence
AK090825	sequence
AK309288	sequence
AK315882	sequence
AK092992	sequence
AF395824	sequence

	Polyadenylation
Identifier	Position	Gene coordinates of cleavage site	Chromosomal coordinates of cleavage site	Pattern	PolyA tail	Accession number	Type
PA1	9	99653	55540548		no	AK314338	Full_length
PA2	9	100305	55539896		no	AK309288	Full_length
PA3	9	100540	55539661		no	AK315882	Full_length
PA4	9	101894	55538307	AATAAA	yes	NM_030796	Cdna
PA5	9	101894	55538307	AATAAA	no	AK075391	Cdna
PA6	9	101894	55538307	AATAAA	yes	BC016650	Cdna
PA7	9	101894	55538307	AATAAA	no	AB097004	Cdna
PA8	9	101894	55538307	AATAAA	yes	AL136610	Cdna
PA9	9	101894	55538307	AATAAA	no	AF395824	Cdna
PA10	9	101894	55538307	AATAAA	no	AK090825	Full_length
PA11	9	101894	55538307	AATAAA	no	AK092992	Full_length

More polyadenylation sites ...

	Exon skipping
Identifier	Position	Transcript
ES1	2	NM_030796 AK225755 XM_001723367 AK075391 AK314338 BC016650 AB097004 AL136610 XM_001129280 CR533483
ES2	3	NM_030796 AK225755 XM_001723367 AK075391 AK314338 BC016650 AB097004 AL136610 XM_001129280 CR533483 AK090825
ES3	4	NM_030796 AK225755 XM_001723367 AK075391 AK314338 BC016650 AB097004 AL136610 XM_001129280 CR533483 AK090825 AK309288
ES4	5	NM_030796 AK225755 XM_001723367 AK075391 AK314338 BC016650 AB097004 AL136610 XM_001129280 CR533483 AK090825 AK309288 AK315882

	Splice site strength
Identifier	Site	Exon	Strength	Alternative	Sequence
S1	5' (donor)	1	7.81	no	GAGgtaggg
S2	5' (donor)	2	5.42	no	TAGgtgcgg
S3	3' (acceptor)	2	-29.11	no	gcaggcgcggagagcccgggGCG
S4	5' (donor)	3	6.66	no	ATGgtagga
S5	3' (acceptor)	3	-30.64	no	ttcctaggagaacaggctccACT
S6	5' (donor)	4	7.44	no	CAGgtttgt
S7	3' (acceptor)	4	-1.89	no	agctgtttttgtcattacacACA
S8	5' (donor)	5	4.83	no	CAGgtgctt
S9	3' (acceptor)	5	-33.93	no	cttgtagcgtcctccatggtAGA
S10	5' (donor)	6	6.69	no	TATgtaagt
S11	3' (acceptor)	6	9.42	no	tttcttgcttctatttgcagTGC
S12	5' (donor)	7	8.37	no	CTGgtaggt
S13	3' (acceptor)	7	13.5	no	gcctgtgcctctctccacagATG
S14	5' (donor)	8	7.16	no	CAGgtcagc
S15	3' (acceptor)	8	9.83	no	cacgtctgtactctcctcagGTT
S16	3' (acceptor)	9	11.2	no	tatgtttgtctgtctttcagGAG

	Conserved exons
Gene identifier mouse	Position human	Position mouse
13866	6	2
13866	7	3
13866	8	4

Report
Exon	Number of supporting transcripts
Transcription initiation & first exon(s)
1	2
2	1
3	1
4	1
5	1
6	1
Transcription termination & last exon(s)
9	11
Exon skipping
2	10
3	11
4	12
5	13

Splicing factors
Splicing factor	Exon array	CLIP data	Exon position
CELF1 (CUG-BP)
DAZAP1
ELAVL1 (HuR)	Yes	Yes
ESRP1/2 (ESRP)	Yes
FUS		Yes
HNRNPA1		Yes
HNRNPA2B1		Yes
HNRNPAB
HNRNPC		Yes
HNRNPF/HNRNPH1	Yes	Yes
HNRNPL	Yes
HNRNPL_2
HNRNPM		Yes
HNRNPU		Yes
MBNL
NOVA1
PTBP1/2 (PTB)	Yes	Yes
QKI
RBFOX2 (FOX2)		Yes
RBM4	Yes
SFRS3 (SRP20)
SFRS6 (SRP55)
SFRS7 (9G8)
SRSF1 (SF2ASF)
SRSF2 (SC35)
SRSF5 (SRP40)
TDP43
TIA1/TIAL1		Yes
TRA2A
TRA2B
YBX1 (YB1)

	Expression
Exon position	Tissues	Cell lines	Cancer cell lines
1	Expression	Expression	Expression
2	Expression	Expression	Expression
3	Expression	Expression	Expression
4	Expression	Expression	Expression
5	Expression	Expression	Expression
6	Expression	Expression	Expression
7	Expression	Expression	Expression
8	Expression	Expression	Expression
9	Expression	Expression	Expression

	Exon-Intron
Position	Type	Gene coordinates	Chromosomal coordinates	Length	Sequence	Features
1	Exon	1 - 237	55639964-55640200	237	sequence	download
1	Intron	238 - 639	55639562-55639963	402	sequence	-
2	Exon	640 - 799	55639402-55639561	160	sequence	download
2	Intron	800 - 19734	55620467-55639401	18935	sequence	-
3	Exon	19735 - 19855	55620346-55620466	121	sequence	download
3	Intron	19856 - 33847	55606354-55620345	13992	sequence	-
4	Exon	33848 - 33895	55606306-55606353	48	sequence	download
4	Intron	33896 - 34813	55605388-55606305	918	sequence	-
5	Exon	34814 - 35007	55605194-55605387	194	sequence	download
5	Intron	35008 - 51377	55588824-55605193	16370	sequence	-
6	Exon	51378 - 51436	55588765-55588823	59	sequence	download
6	Intron	51437 - 74817	55565384-55588764	23381	sequence	-
7	Exon	74818 - 74895	55565306-55565383	78	sequence	download
7	Intron	74896 - 80089	55560112-55565305	5194	sequence	-
8	Exon	80090 - 80226	55559975-55560111	137	sequence	download
8	Intron	80227 - 99462	55540739-55559974	19236	sequence	-
9	Exon	99463 - 101894	55538307-55540738	2432	sequence	download

	5' untranslated regions
	UTR 1	UTR 2	UTR 3	UTR 4	UTR 5
Supporting GenBank accession identifers	NM_030796 AK225755 XM_001723367 AK075391 BC016650 AB097004	AK314338	AK309288	AK092992	AK090825
Length	183	89	118	167	307
Number of ATGs in frame	0	0	0	1	2
Total number of ATGs	0	0	0	2	3
Number of GTGs in frame	2	1	1	1	2
Total number of GTGs	5	3	6	6	8
Number of CTGs in frame	0	0	1	3	1
Total number of CTGs	0	0	4	5	14
Number of micro ORFs in frame	0	0	0	1	2
Total number of micro ORFs	0	0	0	1	2
GC percentage	85	82	64	60	59
Number of pyrimidine tracks	0	0	1	0	1

	3' untranslated regions
	UTR 1	UTR 2
Supporting GenBank accession identifers	NM_030796 AK075391 AB097004 AL136610 AK090825 AF395824 XM_001723367 AK315882 AK309288 XM_001129280 CR533483 AK225755	BC016650 AK092992
Length	2241	2240
Number of ATGs in frame	13	14
Total number of ATGs	36	36
Number of GTGs in frame	23	24
Total number of GTGs	72	72
Number of CTGs in frame	18	17
Total number of CTGs	54	54
GC percentage	50	50
Number of pyrimidine tracks	16	16

	miRNAs
Identifier	Name	Gene coordinates	Chromosomal coordinates	Prediction algorithm
Group 1
M1	hsa-miR-107	99745 - 99752	55540449 - 55540456	pictar
M2	hsa-miR-103	99745 - 99752	55540449 - 55540456	pictar
M3	hsa-miR-1185	99770 - 99776	55540425 - 55540431	pita
M4	hsa-miR-636	99780 - 99787	55540414 - 55540421	pita
M5	hsa-miR-218	99781 - 99788	55540413 - 55540420	pita
M6	hsa-miR-218	99781 - 99788	55540413 - 55540420	pictar
M7	hsa-miR-218	99781 - 99788	55540413 - 55540420	targetscan
M8	hsa-miR-107	99844 - 99851	55540350 - 55540357	pictar
M9	hsa-miR-103	99844 - 99851	55540350 - 55540357	pictar
M10	hsa-miR-107	99847 - 99854	55540347 - 55540354	pictar
M11	hsa-miR-103	99847 - 99854	55540347 - 55540354	pictar
Group 2
M1	hsa-miR-30e-5p	100446 - 100453	55539748 - 55539755	pictar
Group 3
M1	hsa-miR-107	100953 - 100960	55539241 - 55539248	pictar
M2	hsa-miR-218	101219 - 101226	55538975 - 55538982	pictar
M3	hsa-miR-103	101227 - 101234	55538967 - 55538974	pictar
M4	hsa-miR-103	101227 - 101234	55538967 - 55538974	targetscan
M5	hsa-miR-107	101227 - 101234	55538967 - 55538974	targetscan
M6	hsa-miR-107	101227 - 101234	55538967 - 55538974	pictar
M7	hsa-miR-107	101290 - 101297	55538904 - 55538911	pictar
M8	hsa-miR-103	101290 - 101297	55538904 - 55538911	pictar
M9	hsa-miR-218	101310 - 101330	55538871 - 55538891	miranda
M10	hsa-miR-218	101322 - 101329	55538872 - 55538879	pictar
M11	hsa-miR-218	101322 - 101330	55538871 - 55538879	targetscan
M12	hsa-miR-218	101323 - 101329	55538872 - 55538878	pita
M13	hsa-miR-30e	101337 - 101345	55538856 - 55538864	targetscan
M14	hsa-miR-30a	101337 - 101345	55538856 - 55538864	targetscan
M15	hsa-miR-30b	101337 - 101345	55538856 - 55538864	targetscan
M16	hsa-miR-30c	101337 - 101345	55538856 - 55538864	targetscan
M17	hsa-miR-30d	101337 - 101345	55538856 - 55538864	targetscan
M18	hsa-miR-30a-5p	101338 - 101345	55538856 - 55538863	pictar
M19	hsa-miR-30e-5p	101338 - 101345	55538856 - 55538863	pictar
M20	hsa-miR-30d	101338 - 101345	55538856 - 55538863	pictar
M21	hsa-miR-30c	101338 - 101345	55538856 - 55538863	pictar
M22	hsa-miR-30b	101338 - 101345	55538856 - 55538863	pictar
M23	hsa-miR-218	101432 - 101439	55538762 - 55538769	pictar
M24	hsa-miR-218	101432 - 101439	55538762 - 55538769	targetscan
M25	hsa-miR-342-3p	101562 - 101584	55538617 - 55538639	miranda
M26	hsa-miR-103	101794 - 101801	55538400 - 55538407	pictar
M27	hsa-miR-507	101870 - 101876	55538325 - 55538331	pita
M28	hsa-miR-557	101870 - 101876	55538325 - 55538331	pita

	Protein features
Category	Feature identifier	Feature name	Exons	Start on gene	End on gene
Localization	EXONT:000069	ER_retention_signal	1	183	192
Localization	EXONT:000019	Signal_peptide	1,6	184	51389
Localization	EXONT:000067	Nuclear_export_signal	4,6	33860	51386
Localization	EXONT:000069	ER_retention_signal	5	34981	34989
Localization	EXONT:000071	Transmembrane_helix	7,8	74879	80144
Structure	EXONT:000074	Intrinsically_unstructured_polypeptide_region	5	34981	35007
Structure	EXONT:000071	Transmembrane_helix	7,8	74879	80144
Structure	EXONT:000024	Compositionally_biased_region_of_peptide	8,9	80157	99626
PTM	EXONT:000164	O4'-phospho-L-tyrosine	6	51405	51407
PTM	EXONT:000164	O4'-phospho-L-tyrosine	8	80196	80198