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Previous gene FasterDB identifier: 13730 - LANCL2 (GPR69B, TASP) LanC lantibiotic synthetase component C-like 2 (bacterial) Next gene
Gene Close
Symbol LANCL2
Synonyms GPR69B, TASP
Description LanC lantibiotic synthetase component C-like 2 (bacterial)
EnsEMBL link ENSG00000132434
Chromosome 7 - forward strand
Chromosomal location
(UCSC link)		 55433141 - 55501435 (68295bp)
Sequence sequence
Associated transcripts AK095857 NM_018697 AK313326 BC070049 AK225958 AJ278245 AB035966 AF353942 AK307204 AK301747 AL713665 CR620619 CR619072 BC004887
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 4 46 AK225958
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 3 -89 AK225958
ASS2 4 -38 AK225958
ASS3 1 -4 AK095857
NM_018697
AK313326
BC070049
AK225958
AJ278245
AB035966
AF353942
AK301747
AL713665
CR620619
CR619072
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 55433141 AK095857
NM_018697
P2 1 257 55433397 AK313326
P3 1 594 55433734 AK307204
P4 1 595 55433735 AK301747
Protein prediction Close
 Transcript name   Sequence 
AK095857 sequence
NM_018697 sequence
AK313326 sequence
BC070049 sequence
AK225958 sequence
AJ278245 sequence
AB035966 sequence
AF353942 sequence
AK307204 sequence
AK301747 sequence
AL713665 sequence
CR620619 sequence
CR619072 sequence
BC004887 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 3 26748 55459888 no AK307204 Full_length
PA2 10 65873 55499013 no AK313326 Full_length
PA3 10 66082 55499222 AATATA no AK301747 Full_length
PA4 10 68295 55501435 no NM_018697 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
ES1 2 AK095857
NM_018697
AK313326
BC070049
AK225958
AJ278245
AB035966
AF353942
AK301747
AL713665
CR620619
CR619072
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 -11.8 no TGAgtcggc
S2 5' (donor) 1 10.47 yes AAGgtgagt
S3 5' (donor) 2 8.55 no GAGgtatga
S4 3' (acceptor) 2 -5.78 no ggttttctttttccactgagGTA
S5 5' (donor) 3 10.07 no CAGgtgagg
S6 3' (acceptor) 3 8.72 no tctcttcttttggatctcagATC
S7 5' (donor) 3 -28.43 yes CCAgaccaa
S8 5' (donor) 4 8.4 no AAAgtgagt
S9 3' (acceptor) 4 1.27 no ggggtgggaaattattccagGCA
S10 5' (donor) 4 -10.54 yes AAActcaga
S11 3' (acceptor) 4 -15.25 yes taccgggtcacatgtgaccaAAC
S12 5' (donor) 5 6.36 no GAGgtacta
S13 3' (acceptor) 5 3.18 no taatttttcttattggttagACT
S14 5' (donor) 6 10.28 no CAGgtaggt
S15 3' (acceptor) 6 11.46 no ctgtcttgttatctctgtagGTA
S16 5' (donor) 7 8.68 no AAGgtcagt
S17 3' (acceptor) 7 6.93 no tcatttttgtttgtttaaagCCG
S18 5' (donor) 8 9.16 no AAGgtgagg
S19 3' (acceptor) 8 6.79 no tttgtttttaatttgcccagGTC
S20 5' (donor) 9 10.57 no AAGgtaaga
S21 3' (acceptor) 9 6.75 no agaaatccctttcttttcagTTT
S22 3' (acceptor) 10 8.74 no ctcctcattttacattgcagGCA
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
13793 3 2
13793 4 3
13793 5 4
13793 6 5
13793 7 6
13793 8 7
13793 9 8
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 4
 Transcription termination & last exon(s) 
3 1
10 3
 Exon skipping 
2 12
 Alternative 3' splice sites 
4 1
 Alternative 5' splice sites 
1 1
3 1
4 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 786 55433141 - 55433926 786 sequence download
1 Intron 787 - 1829 55433927 - 55434969 1043 sequence -
2 Exon 1830 - 2181 55434970 - 55435321 352 sequence download
2 Intron 2182 - 26345 55435322 - 55459485 24164 sequence -
3 Exon 26346 - 26463 55459486 - 55459603 118 sequence download
3 Intron 26464 - 32975 55459604 - 55466115 6512 sequence -
4 Exon 32976 - 33183 55466116 - 55466323 208 sequence download
4 Intron 33184 - 34509 55466324 - 55467649 1326 sequence -
5 Exon 34510 - 34657 55467650 - 55467797 148 sequence download
5 Intron 34658 - 35726 55467798 - 55468866 1069 sequence -
6 Exon 35727 - 35873 55468867 - 55469013 147 sequence download
6 Intron 35874 - 46459 55469014 - 55479599 10586 sequence -
7 Exon 46460 - 46642 55479600 - 55479782 183 sequence download
7 Intron 46643 - 59806 55479783 - 55492946 13164 sequence -
8 Exon 59807 - 59983 55492947 - 55493123 177 sequence download
8 Intron 59984 - 62927 55493124 - 55496067 2944 sequence -
9 Exon 62928 - 63000 55496068 - 55496140 73 sequence download
9 Intron 63001 - 65778 55496141 - 55498918 2778 sequence -
10 Exon 65779 - 68295 55498919 - 55501435 2517 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2   UTR 3   UTR 4 
 Supporting GenBank
accession identifers 		 AK095857
NM_018697
BC070049
 AK313326
 AK307204
 AK225958
AJ278245
AB035966
AF353942
 Length  578 323 39 826
 Number of ATGs in frame  2 1 0 3
 Total number of ATGs  2 1 0 12
 Number of GTGs in frame  3 1 2 9
 Total number of GTGs  11 7 2 24
 Number of CTGs in frame  2 1 0 3
 Total number of CTGs  8 4 0 8
 Number of micro ORFs in frame  2 1 0 0
 Total number of micro ORFs  2 1 0 4
 GC percentage  75 76 56 61
 Number of pyrimidine tracks  6 3 0 5
Close 3' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 		 AK307204
 NM_018697
AJ278245
BC070049
AK225958
AK301747
AK095857
AL713665
BC004887
AB035966
AF353942
CR620619
CR619072
 Length  658 2422
 Number of ATGs in frame  1 20
 Total number of ATGs  9 44
 Number of GTGs in frame  8 13
 Total number of GTGs  20 50
 Number of CTGs in frame  6 19
 Total number of CTGs  13 47
 GC percentage  48 44
 Number of pyrimidine tracks  4 10
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-133a 65892 - 65913 55499032 - 55499053 miranda
M2 hsa-miR-133b 65892 - 65913 55499032 - 55499053 miranda
M3 hsa-miR-133a 65906 - 65914 55499046 - 55499054 targetscan
M4 hsa-miR-133b 65906 - 65914 55499046 - 55499054 targetscan
M5 hsa-miR-592 65936 - 65942 55499076 - 55499082 pita
Group 2
M1 hsa-miR-494 66101 - 66107 55499241 - 55499247 pita
M2 hsa-miR-494 66101 - 66108 55499241 - 55499248 targetscan
M3 hsa-miR-495 66112 - 66119 55499252 - 55499259 pita
M4 hsa-miR-411 66875 - 66895 55500015 - 55500035 miranda
M5 hsa-miR-186 66882 - 66889 55500022 - 55500029 pictar
M6 hsa-miR-377 66958 - 66979 55500098 - 55500119 miranda
M7 hsa-miR-224 66963 - 66982 55500103 - 55500122 miranda
M8 hsa-miR-371-5p 68238 - 68244 55501378 - 55501384 pita
M9 hsa-miR-548b-3p 68243 - 68250 55501383 - 55501390 pita
M10 hsa-miR-186 68246 - 68253 55501386 - 55501393 pictar
M11 hsa-miR-495 68255 - 68262 55501395 - 55501402 targetscan
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Catalytic EXONT:006277 Six-hairpin glycosidase 7,8,9 46466 62948
Localization EXONT:000064 Nuclear_localization_signal 1 597 608
Localization EXONT:000065 Endosomal_localization_signal 6 35781 35801
Localization EXONT:000066 Lysosomal_localization_signal 6 35781 35801
Localization EXONT:000064 Nuclear_localization_signal 7 46529 46540
Localization EXONT:000064 Nuclear_localization_signal 9 62967 62987
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 1 579 620
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 1 720 761
PTM EXONT:000200 N-myristoylglycine 1 582 584
PTM EXONT:000164 O4'-phospho-L-tyrosine 4 33047 33049
PTM EXONT:000797 Ubiquitinylated lysine 4 33143 33145
PTM EXONT:000164 O4'-phospho-L-tyrosine 5 34571 34573
PTM EXONT:000164 O4'-phospho-L-tyrosine 7 46517 46519
PTM EXONT:000180 N-acetylated L-lysine 7 46532 46534
PTM EXONT:000192 N6-acetyl-L-lysine 7 46532 46534
Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2
Gene LANCL2 Gene LANCL2

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Extended region