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Previous gene FasterDB identifier: 13185 - UBA7 (D8, UBA1B, UBE1L, UBE2) ubiquitin-like modifier activating enzyme 7 Next gene
Gene Close
Symbol UBA7
Synonyms D8, UBA1B, UBE1L, UBE2
Description ubiquitin-like modifier activating enzyme 7
EnsEMBL link ENSG00000182179
Chromosome 3 - reverse strand
Chromosomal location
(UCSC link)		 49842639 - 49851391 (8753bp)
Sequence sequence
Associated transcripts NM_003335 L13852 BC006378 BT007026
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 49851391 NM_003335
Protein prediction Close
 Transcript name   Sequence 
NM_003335 sequence
L13852 sequence
BC006378 sequence
BT007026 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 24 8753 49842639 AATAAA yes NM_003335 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
No data
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 2.85 no GCTgtgagg
S2 5' (donor) 2 10.86 no CAGgtaagt
S3 3' (acceptor) 2 12.09 no cttctgcttcccatccacagGTA
S4 5' (donor) 3 7.16 no CAGgtcagc
S5 3' (acceptor) 3 9.57 no tgcactggctctctccctagTTT
S6 5' (donor) 4 7.93 no GGGgtgagt
S7 3' (acceptor) 4 8.73 no tgatcactgtgtccacccagGTG
S8 5' (donor) 5 8.56 no CAGgtgggt
S9 3' (acceptor) 5 6.26 no cccctaccaccccatctcagGCA
S10 5' (donor) 6 7.79 no GGGgtaagc
S11 3' (acceptor) 6 4.77 no ccaagcctcctcctacccagGGC
S12 5' (donor) 7 7.83 no CATgtgagt
S13 3' (acceptor) 7 0.87 no ctagactggaactccctcagAGG
S14 5' (donor) 8 7.21 no CCTgtgagt
S15 3' (acceptor) 8 2.61 no tgagccaggtgcccttgcagAAG
S16 5' (donor) 9 7.93 no AAGgtgggc
S17 3' (acceptor) 9 2.98 no ccacagagtcctaccaacagGTT
S18 5' (donor) 10 7.54 no CTGgtgaga
S19 3' (acceptor) 10 4.47 no gcctgaagtgctgcccctagGCA
S20 5' (donor) 11 8.05 no CTGgtgagc
S21 3' (acceptor) 11 10.47 no accccgtctctgtcccctagAGA
S22 5' (donor) 12 6.05 no GGTgtgagt
S23 3' (acceptor) 12 8.33 no aaggctgttcctgccaacagGTG
S24 5' (donor) 13 8.4 no CCCgtgagt
S25 3' (acceptor) 13 8.91 no tcttcctgccttcttcccagAGA
S26 5' (donor) 14 9.79 no CAGgtagga
S27 3' (acceptor) 14 7.77 no acccactgctcccttgccagGGC
S28 5' (donor) 15 5.42 no ACAgtaagg
S29 3' (acceptor) 15 10.36 no tcttcctccctcctccacagTGG
S30 5' (donor) 16 2.99 no AAAgtgtgt
S31 3' (acceptor) 16 13.4 no acttcctcctctctctgcagGGC
S32 5' (donor) 17 9.1 no CAAgtgagt
S33 3' (acceptor) 17 8.15 no gcttctacttacctacctagGTG
S34 5' (donor) 18 6.9 no TTGgtgagg
S35 3' (acceptor) 18 7.48 no tgctcttggtctggctgcagGAC
S36 5' (donor) 19 8.23 no AAGgtgggt
S37 3' (acceptor) 19 10.23 no aacatcccctcccctgacagGCC
S38 5' (donor) 20 8.66 no CAGgtaacc
S39 3' (acceptor) 20 7.18 no ctttgacttgggccttacagGAT
S40 5' (donor) 21 9.44 no ACGgtgagc
S41 3' (acceptor) 21 6.68 no aaatctcttgtccttggcagAGC
S42 5' (donor) 22 6.46 no CAGgtgtgc
S43 3' (acceptor) 22 6.88 no cctcctctacctcatcccagTTC
S44 5' (donor) 23 9.6 no CAGgtgagc
S45 3' (acceptor) 23 11.19 no gtctgacctttctcctctagGAG
S46 3' (acceptor) 24 3.77 no cctaaacccacccctaccagGGT
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
8477 2 2
8477 3 3
8477 4 4
8477 5 5
8477 7 7
8477 8 8
8477 9 9
8477 10 10
8477 11 11
8477 12 12
8477 13 13
8477 14 14
8477 15 15
8477 16 16
8477 17 17
8477 18 18
8477 19 19
8477 20 20
8477 21 21
8477 22 22
8477 23 23
8477 24 24
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 1
 Transcription termination & last exon(s) 
24 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
11 Expression Expression Expression
12 Expression Expression Expression
13 Expression Expression Expression
14 Expression Expression Expression
15 Expression Expression Expression
16 Expression Expression Expression
17 Expression Expression Expression
18 Expression Expression Expression
19 Expression Expression Expression
20 Expression Expression Expression
21 Expression Expression Expression
22 Expression Expression Expression
23 Expression Expression Expression
24 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 227 49851165-49851391 227 sequence download
1 Intron 228 - 311 49851081-49851164 84 sequence -
2 Exon 312 - 480 49850912-49851080 169 sequence download
2 Intron 481 - 575 49850817-49850911 95 sequence -
3 Exon 576 - 710 49850682-49850816 135 sequence download
3 Intron 711 - 790 49850602-49850681 80 sequence -
4 Exon 791 - 897 49850495-49850601 107 sequence download
4 Intron 898 - 1220 49850172-49850494 323 sequence -
5 Exon 1221 - 1311 49850081-49850171 91 sequence download
5 Intron 1312 - 1415 49849977-49850080 104 sequence -
6 Exon 1416 - 1551 49849841-49849976 136 sequence download
6 Intron 1552 - 1752 49849640-49849840 201 sequence -
7 Exon 1753 - 1850 49849542-49849639 98 sequence download
7 Intron 1851 - 1942 49849450-49849541 92 sequence -
8 Exon 1943 - 2089 49849303-49849449 147 sequence download
8 Intron 2090 - 2503 49848889-49849302 414 sequence -
9 Exon 2504 - 2686 49848706-49848888 183 sequence download
9 Intron 2687 - 2867 49848525-49848705 181 sequence -
10 Exon 2868 - 2975 49848417-49848524 108 sequence download
10 Intron 2976 - 3126 49848266-49848416 151 sequence -
11 Exon 3127 - 3207 49848185-49848265 81 sequence download
11 Intron 3208 - 3286 49848106-49848184 79 sequence -
12 Exon 3287 - 3442 49847950-49848105 156 sequence download
12 Intron 3443 - 3530 49847862-49847949 88 sequence -
13 Exon 3531 - 3696 49847696-49847861 166 sequence download
13 Intron 3697 - 3775 49847617-49847695 79 sequence -
14 Exon 3776 - 3981 49847411-49847616 206 sequence download
14 Intron 3982 - 4079 49847313-49847410 98 sequence -
15 Exon 4080 - 4144 49847248-49847312 65 sequence download
15 Intron 4145 - 4233 49847159-49847247 89 sequence -
16 Exon 4234 - 4417 49846975-49847158 184 sequence download
16 Intron 4418 - 4494 49846898-49846974 77 sequence -
17 Exon 4495 - 4569 49846823-49846897 75 sequence download
17 Intron 4570 - 4799 49846593-49846822 230 sequence -
18 Exon 4800 - 4983 49846409-49846592 184 sequence download
18 Intron 4984 - 5490 49845902-49846408 507 sequence -
19 Exon 5491 - 5573 49845819-49845901 83 sequence download
19 Intron 5574 - 5846 49845546-49845818 273 sequence -
20 Exon 5847 - 5939 49845453-49845545 93 sequence download
20 Intron 5940 - 6031 49845361-49845452 92 sequence -
21 Exon 6032 - 6223 49845169-49845360 192 sequence download
21 Intron 6224 - 7793 49843599-49845168 1570 sequence -
22 Exon 7794 - 7886 49843506-49843598 93 sequence download
22 Intron 7887 - 7961 49843431-49843505 75 sequence -
23 Exon 7962 - 8062 49843330-49843430 101 sequence download
23 Intron 8063 - 8521 49842871-49843329 459 sequence -
24 Exon 8522 - 8753 49842639-49842870 232 sequence download
Close  5' untranslated regions 
 UTR 1 
 Supporting GenBank
accession identifers 		 NM_003335
L13852
BC006378
 Length  171
 Number of ATGs in frame  0
 Total number of ATGs  0
 Number of GTGs in frame  3
 Total number of GTGs  8
 Number of CTGs in frame  0
 Total number of CTGs  1
 Number of micro ORFs in frame  0
 Total number of micro ORFs  0
 GC percentage  56
 Number of pyrimidine tracks  2
Close 3' untranslated regions 
 UTR 1 
 Supporting GenBank
accession identifers 		 NM_003335
L13852
BC006378
 Length  102
 Number of ATGs in frame  0
 Total number of ATGs  2
 Number of GTGs in frame  0
 Total number of GTGs  2
 Number of CTGs in frame  0
 Total number of CTGs  0
 GC percentage  54
 Number of pyrimidine tracks  0
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
No data
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Catalytic EXONT:002321 UBA/THIF-type NAD/FAD binding fold 2,3,4,5 352 1227
Catalytic EXONT:002321 UBA/THIF-type NAD/FAD binding fold 11,12,13,14 3190 3861
Catalytic EXONT:008086 Ubiquitin-activating enzyme, E1, active site 14 3931 3957
Catalytic EXONT:001982 Ubiquitin-activating enzyme repeat 17,18 4552 4931
Catalytic EXONT:001982 Ubiquitin-activating enzyme repeat 19,20,21 5565 6130
Binding EXONT:000062 Nucleotide_binding_site 12 3299 3388
Binding EXONT:001982 Ubiquitin-activating enzyme repeat 17,18 4552 4931
Binding EXONT:001982 Ubiquitin-activating enzyme repeat 19,20,21 5565 6130
Localization EXONT:000067 Nuclear_export_signal 5 1222 1263
Localization EXONT:000064 Nuclear_localization_signal 7 1824 1841
Localization EXONT:000017 Cilia targeting sequence 16 4307 4321
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 1 172 195
Structure EXONT:000027 Polypeptide_repeat 2,3,4,5 322 1230
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 9 2543 2578
Structure EXONT:000027 Polypeptide_repeat 11,12,13,14 3163 3867
Structure EXONT:001982 Ubiquitin-activating enzyme repeat 17,18 4552 4931
Structure EXONT:001982 Ubiquitin-activating enzyme repeat 19,20,21 5565 6130
PTM EXONT:000164 O4'-phospho-L-tyrosine 1 214 216
PTM EXONT:000161 O-phospho-L-serine 2 325 327
PTM EXONT:000164 O4'-phospho-L-tyrosine 13 3603 3605
PTM EXONT:000164 O4'-phospho-L-tyrosine 13 3633 3635
PTM EXONT:000164 O4'-phospho-L-tyrosine 14 3805 3807
PTM EXONT:000161 O-phospho-L-serine 21 6143 6145
PTM EXONT:000161 O-phospho-L-serine 21 6158 6160
PTM EXONT:000164 O4'-phospho-L-tyrosine 21 6182 6184
PTM EXONT:000164 O4'-phospho-L-tyrosine 21 6194 6196
Unclassified EXONT:002478 NAD(P)-binding domain 1,2,3,4,5,6 202 1514
Unclassified EXONT:005451 Molybdenum cofactor biosynthesis, MoeB 1,2,3,4,5,6,7,8,9,10 202 2936
Unclassified EXONT:002478 NAD(P)-binding domain 7,8,9,10 1824 2936
Unclassified EXONT:005451 Molybdenum cofactor biosynthesis, MoeB 10,11,12,13,14,15,16,17,18,19,20,21 2972 6187
Unclassified EXONT:002478 NAD(P)-binding domain 11,12,13,14 3133 3939
Unclassified EXONT:008756 Ubiquitin-activating enzyme 14,15 3871 4112
Unclassified EXONT:009839 Ubiquitin-like 1 activating enzyme, catalytic cysteine domain 14,15,16,17,18,19,20,21 3940 6052
Unclassified EXONT:002478 NAD(P)-binding domain 21 6059 6148
Unclassified EXONT:008540 Ubiquitin-activating enzyme e1, C-terminal 21,22,23,24 6149 8636
Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7
Gene UBA7 Gene UBA7

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 20Exon 21Exon 22Exon 23Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 20Exon 21Exon 22Exon 23Exon 24Extended region