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Previous gene FasterDB identifier: 2263 - KCNJ4 (HIR, hIRK2, HRK1, IRK3, Kir2.3) potassium inwardly-rectifying channel, subfamily J, member 4 Next gene
Gene Close
Symbol KCNJ4
Synonyms HIR, hIRK2, HRK1, IRK3, Kir2.3
Description potassium inwardly-rectifying channel, subfamily J, member 4
EnsEMBL link ENSG00000168135
Chromosome 22 - reverse strand
Chromosomal location
(UCSC link)
38822332 - 38851211 (28880bp)
Sequence sequence
Associated transcripts BC032562 NM_152868 U24056 BC039618 CR456507 S72503 U07364 NM_004981
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 38851211 BC032562
P2 2 11178 38840034 S72503
Protein prediction Close
 Transcript name   Sequence 
BC032562 sequence
NM_152868 sequence
U24056 sequence
BC039618 sequence
CR456507 sequence
S72503 sequence
U07364 sequence
NM_004981 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 3 28880 38822332 TATAAA no NM_152868 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
ES1 2 BC032562
NM_152868
U24056
BC039618
CR456507
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 8.99 no GCGgtaagc
S2 5' (donor) 2 6.18 no TTGgtgcgt
S3 3' (acceptor) 2 -25.51 no aagcggtggagtcttggagaAGA
S4 3' (acceptor) 3 11.01 no gtccggcttctcctccgcagGCC
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
16592 3 2
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 1
2 1
 Transcription termination & last exon(s) 
3 1
 Exon skipping 
2 5
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 226 38850986-38851211 226 sequence download
1 Intron 227 - 11177 38840035-38850985 10951 sequence -
2 Exon 11178 - 11236 38839976-38840034 59 sequence download
2 Intron 11237 - 27035 38824177-38839975 15799 sequence -
3 Exon 27036 - 28880 38822332-38824176 1845 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 
NM_152868
U24056
CR456507
S72503
U07364
NM_004981
 Length  257 98
 Number of ATGs in frame  0 0
 Total number of ATGs  1 0
 Number of GTGs in frame  1 1
 Total number of GTGs  1 1
 Number of CTGs in frame  0 0
 Total number of CTGs  1 2
 Number of micro ORFs in frame  0 0
 Total number of micro ORFs  1 0
 GC percentage  79 55
 Number of pyrimidine tracks  2 0
Close 3' untranslated regions 
 UTR 1 
 Supporting GenBank
accession identifers 
NM_152868
U07364
NM_004981
S72503
U24056
CR456507
 Length  468
 Number of ATGs in frame  2
 Total number of ATGs  5
 Number of GTGs in frame  3
 Total number of GTGs  15
 Number of CTGs in frame  3
 Total number of CTGs  9
 GC percentage  61
 Number of pyrimidine tracks  6
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-455-3p 28728 - 28734 38822478 - 38822484 pita
M2 hsa-miR-339 28766 - 28773 38822439 - 38822446 pictar
M3 hsa-miR-136 28843 - 28863 38822349 - 38822369 miranda
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Binding EXONT:001885 Protein binding 3 28323 28409
Localization EXONT:000064 Nuclear_localization_signal 3 27111 27131
Localization EXONT:000071 Transmembrane_helix 3 27240 27317
Localization EXONT:000071 Transmembrane_helix 3 27432 27500
Localization EXONT:000032 Intramembrane_polypeptide_region 3 27435 27491
Localization EXONT:000071 Transmembrane_helix 3 27519 27587
Localization EXONT:000064 Nuclear_localization_signal 3 27732 27755
Localization EXONT:000067 Nuclear_export_signal 3 28344 28379
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 3 27075 27134
Structure EXONT:000071 Transmembrane_helix 3 27240 27317
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 3 27348 27398
Structure EXONT:000024 Compositionally_biased_region_of_peptide 3 27378 27389
Structure EXONT:000071 Transmembrane_helix 3 27432 27500
Structure EXONT:000037 Peptide_helix 3 27435 27470
Structure EXONT:000032 Intramembrane_polypeptide_region 3 27435 27491
Structure EXONT:000071 Transmembrane_helix 3 27519 27587
Structure EXONT:000024 Compositionally_biased_region_of_peptide 3 28158 28178
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 3 28218 28250
Structure EXONT:000024 Compositionally_biased_region_of_peptide 3 28221 28271
PTM EXONT:000162 O-phospho-L-threonine 3 27231 27233
PTM EXONT:000164 O4'-phospho-L-tyrosine 3 27774 27776
Unclassified EXONT:002181 Immunoglobulin E-set 3 27552 28145
Unclassified EXONT:006695 Potassium channel, inwardly rectifying, Kir, cytoplasmic 3 27573 28145
Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4
Gene KCNJ4 Gene KCNJ4

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Exon 1Exon 2Exon 1Exon 2Exon 3Extended region