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Previous gene FasterDB identifier: 13648 - MST1R (CD136, CDw136, PTK8, RON) macrophage stimulating 1 receptor (c-met-related tyrosine kinase) Next gene
Gene Close
Symbol MST1R
Synonyms CD136, CDw136, PTK8, RON
Description macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
EnsEMBL link ENSG00000164078
Chromosome 3 - reverse strand
Chromosomal location
(UCSC link)		 49924438 - 49941306 (16869bp)
Sequence sequence
Associated transcripts NM_002447 X70040 EU826582 EU826583 EU826584 EU826585 AK303234
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 10 3 NM_002447
X70040
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 49941306 NM_002447
P2 10 7516 49933791 AK303234
Protein prediction Close
 Transcript name   Sequence 
NM_002447 sequence
X70040 sequence
EU826582 sequence
EU826583 sequence
EU826584 sequence
EU826585 sequence
AK303234 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 2 4868 49936439 no EU826582 Cdna
PA2 5 5887 49935420 no EU826583 Cdna
PA3 5 5887 49935420 no EU826585 Cdna
PA4 10 7754 49933553 no EU826584 Cdna
PA5 20 16709 49924598 no AK303234 Full_length
PA6 20 16869 49924438 AATAAA yes NM_002447 Cdna
PA7 20 16869 49924438 AATAAA yes X70040 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
ES1 2 EU826583
ES2 3 EU826583
ES3 11 AK303234
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 8.8 no CCGgtaagc
S2 5' (donor) 2 8.56 no CAGgtgggt
S3 3' (acceptor) 2 5.77 no ccttccctgacctttcccagCCT
S4 5' (donor) 3 10.07 no CAGgtgagg
S5 3' (acceptor) 3 7.52 no tcacatctgacctgtcctagGTG
S6 5' (donor) 4 8.98 no GAGgtatgg
S7 3' (acceptor) 4 12.21 no cacctgtctttcacccacagGTT
S8 5' (donor) 5 7.09 no CAGgtacaa
S9 3' (acceptor) 5 8.52 no ggctgtttcccccatttcagTTC
S10 5' (donor) 6 7.61 no ATGgtgagg
S11 3' (acceptor) 6 5.08 no gggttcccctggtgccccagACC
S12 5' (donor) 7 11.81 no ACGgtaagt
S13 3' (acceptor) 7 8.27 no ccacctctatgtcctcttagGAG
S14 5' (donor) 8 5.61 no CATgtaagc
S15 3' (acceptor) 8 10.36 no ccaatctcttgttcctgtagGGT
S16 5' (donor) 9 9.25 no AGGgtgagt
S17 3' (acceptor) 9 8.21 no caccctaccctcttccacagCAA
S18 5' (donor) 10 11.08 no GAGgtaagt
S19 3' (acceptor) 10 2.88 no cactctcatattggtcccagCAG
S20 5' (donor) 11 9.88 no CAGgtaggc
S21 3' (acceptor) 11 6.79 no cctcatgaccctctctgcagTAT
S22 5' (donor) 12 8.83 no TAGgtgagt
S23 3' (acceptor) 12 8.19 no gagttgccacctgcccccagGTC
S24 5' (donor) 13 6.29 no TTGgtgaga
S25 3' (acceptor) 13 6.23 no caaggattctctttccacagTTC
S26 5' (donor) 14 5.28 no AAGgtgtgg
S27 3' (acceptor) 14 11.77 no ctcattccctctccccacagCAC
S28 5' (donor) 15 9.9 no GTCgtaagt
S29 3' (acceptor) 15 5.35 no cattatgcacctcacaccagGCC
S30 5' (donor) 16 6.55 no CGGgtcagt
S31 3' (acceptor) 16 7.68 no tgacttgcgctgctctgcagGCA
S32 5' (donor) 17 3.73 no CATgtgaga
S33 3' (acceptor) 17 7.8 no caacccacctgtgcccccagAAC
S34 5' (donor) 18 6.13 no GTGgtgagg
S35 3' (acceptor) 18 5.07 no atcctctccctacccctaagGCT
S36 5' (donor) 19 7 no TCTgtgagt
S37 3' (acceptor) 19 10.53 no tcacctccccctttccacagTGG
S38 3' (acceptor) 20 11.72 no acatccctttcccccaacagGTA
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
8345 1 1
8345 2 2
8345 3 3
8345 4 4
8345 5 5
8345 6 6
8345 7 7
8345 8 8
8345 9 9
8345 10 10
8345 11 11
8345 12 12
8345 14 13
8345 15 14
8345 16 15
8345 17 16
8345 18 17
8345 19 18
8345 20 19
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 1
10 1
 Transcription termination & last exon(s) 
2 1
5 2
10 1
20 3
 Exon skipping 
2 1
3 1
11 1
 Alternative 3' splice sites 
10 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
11 Expression Expression Expression
12 Expression Expression Expression
13 Expression Expression Expression
14 Expression Expression Expression
15 Expression Expression Expression
16 Expression Expression Expression
17 Expression Expression Expression
18 Expression Expression Expression
19 Expression Expression Expression
20 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 1494 49939813-49941306 1494 sequence download
1 Intron 1495 - 4610 49936697-49939812 3116 sequence -
2 Exon 4611 - 4799 49936508-49936696 189 sequence download
2 Intron 4800 - 4878 49936429-49936507 79 sequence -
3 Exon 4879 - 5007 49936300-49936428 129 sequence download
3 Intron 5008 - 5185 49936122-49936299 178 sequence -
4 Exon 5186 - 5356 49935951-49936121 171 sequence download
4 Intron 5357 - 5662 49935645-49935950 306 sequence -
5 Exon 5663 - 5823 49935484-49935644 161 sequence download
5 Intron 5824 - 6188 49935119-49935483 365 sequence -
6 Exon 6189 - 6354 49934953-49935118 166 sequence download
6 Intron 6355 - 6457 49934850-49934952 103 sequence -
7 Exon 6458 - 6594 49934713-49934849 137 sequence download
7 Intron 6595 - 6983 49934324-49934712 389 sequence -
8 Exon 6984 - 7145 49934162-49934323 162 sequence download
8 Intron 7146 - 7240 49934067-49934161 95 sequence -
9 Exon 7241 - 7334 49933973-49934066 94 sequence download
9 Intron 7335 - 7466 49933841-49933972 132 sequence -
10 Exon 7467 - 7679 49933628-49933840 213 sequence download
10 Intron 7680 - 7766 49933541-49933627 87 sequence -
11 Exon 7767 - 7913 49933394-49933540 147 sequence download
11 Intron 7914 - 7993 49933314-49933393 80 sequence -
12 Exon 7994 - 8159 49933148-49933313 166 sequence download
12 Intron 8160 - 8325 49932982-49933147 166 sequence -
13 Exon 8326 - 8427 49932880-49932981 102 sequence download
13 Intron 8428 - 8500 49932807-49932879 73 sequence -
14 Exon 8501 - 8707 49932600-49932806 207 sequence download
14 Intron 8708 - 12035 49929272-49932599 3328 sequence -
15 Exon 12036 - 12116 49929191-49929271 81 sequence download
15 Intron 12117 - 12293 49929014-49929190 177 sequence -
16 Exon 12294 - 12475 49928832-49929013 182 sequence download
16 Intron 12476 - 12567 49928740-49928831 92 sequence -
17 Exon 12568 - 12677 49928630-49928739 110 sequence download
17 Intron 12678 - 13223 49928084-49928629 546 sequence -
18 Exon 13224 - 13389 49927918-49928083 166 sequence download
18 Intron 13390 - 13813 49927494-49927917 424 sequence -
19 Exon 13814 - 13950 49927357-49927493 137 sequence download
19 Intron 13951 - 16311 49924996-49927356 2361 sequence -
20 Exon 16312 - 16869 49924438-49924995 558 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 		 NM_002447
X70040
 AK303234
 Length  264 731
 Number of ATGs in frame  0 0
 Total number of ATGs  0 14
 Number of GTGs in frame  5 20
 Total number of GTGs  6 35
 Number of CTGs in frame  1 7
 Total number of CTGs  4 17
 Number of micro ORFs in frame  0 0
 Total number of micro ORFs  0 8
 GC percentage  69 56
 Number of pyrimidine tracks  0 4
Close 3' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 		 NM_002447
AK303234
 X70040
 Length  302 300
 Number of ATGs in frame  2 0
 Total number of ATGs  5 5
 Number of GTGs in frame  7 1
 Total number of GTGs  12 12
 Number of CTGs in frame  1 3
 Total number of CTGs  7 7
 GC percentage  54 53
 Number of pyrimidine tracks  4 4
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
No data
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Catalytic EXONT:009061 Tyrosine-protein kinase, catalytic domain 14,15,16,17,18,19,20 8680 16387
Catalytic EXONT:002406 Protein kinase domain 14,15,16,17,18,19,20 8680 16399
Catalytic EXONT:002705 Serine-threonine/tyrosine-protein kinase catalytic domain 14,15,16,17,18,19,20 8689 16381
Catalytic EXONT:002212 Protein kinase-like domain 14,15,16,17,18,19,20 8689 16507
Catalytic EXONT:005257 Tyrosine-protein kinase, active site 17,18 12643 13227
Receptor EXONT:007890 Plexin-like fold 4 5201 5344
Binding EXONT:002928 Sema domain 1,2,3,4,5 355 5722
Binding EXONT:002929 WD40/YVTN repeat-like-containing domain 1,2,3,4 403 5230
Binding EXONT:003419 IPT domain 4,5,6 5339 6354
Binding EXONT:003419 IPT domain 7,8 6458 7101
Binding EXONT:003419 IPT domain 8,9,10 7105 7649
Binding EXONT:009061 Tyrosine-protein kinase, catalytic domain 14,15,16,17,18,19,20 8680 16387
Binding EXONT:002406 Protein kinase domain 14,15,16,17,18,19,20 8680 16399
Binding EXONT:002705 Serine-threonine/tyrosine-protein kinase catalytic domain 14,15,16,17,18,19,20 8689 16381
Binding EXONT:007898 Protein kinase, ATP binding site 14,15 8698 12106
Localization EXONT:000064 Nuclear_localization_signal 1 1174 1191
Localization EXONT:000071 Transmembrane_helix 12 8075 8143
Localization EXONT:000064 Nuclear_localization_signal 16 12413 12430
Localization EXONT:000064 Nuclear_localization_signal 19 13850 13867
Structure EXONT:007890 Plexin-like fold 4 5201 5344
Structure EXONT:003160 Plexin 4 5216 5341
Structure EXONT:000071 Transmembrane_helix 12 8075 8143
Unclassified EXONT:002181 Immunoglobulin E-set 4,5 5333 5815
Unclassified EXONT:002625 Immunoglobulin-like fold 4,5,6 5339 6297
Unclassified EXONT:002181 Immunoglobulin E-set 6,7,8,9,10 6349 7613
Unclassified EXONT:002625 Immunoglobulin-like fold 7,8,9 6458 7310
Unclassified EXONT:002625 Immunoglobulin-like fold 11,12 7767 8008
Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R
Gene MST1R Gene MST1R

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 20Extended region