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Previous gene FasterDB identifier: 17385 - CCDC45 (DKFZp667E1824) coiled-coil domain containing 45 Next gene
Gene Close
Symbol CCDC45
Synonyms DKFZp667E1824
Description coiled-coil domain containing 45
EnsEMBL link ENSG00000141325
Chromosome 17 - forward strand
Chromosomal location
(UCSC link)		 62502880 - 62534067 (31188bp)
Sequence sequence
Associated transcripts AK057326 AK316257 AK290587 AK297409 BC009518 NM_138363 AL832822 BX641136 BC029461
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 4 19 AK057326
AK316257
AK290587
AK297409
BC009518
NM_138363
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 13 -4 AK057326
AK290587
AK297409
BC009518
NM_138363
Intron retentions Close
 Identifier   Position   Transcript 
IR1 17 BX641136
IR2 19 BX641136
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 62502880 AK057326
P2 1 231 62503110 AK316257
P3 1 235 62503114 AK290587
P4 1 274 62503153 AK297409
P5 17 27255 62530134 BX641136
P6 18 29371 62532250 BC029461
Protein prediction Close
 Transcript name   Sequence 
AK057326 sequence
AK316257 sequence
AK290587 sequence
AK297409 sequence
BC009518 sequence
NM_138363 sequence
AL832822 sequence
BX641136 sequence
BC029461 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 9 19024 62521903 no AK316257 Full_length
PA2 15 26225 62529104 no AK057326 Full_length
PA3 20 31188 62534067 AATAAA yes BC029461 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
ES1 5 AK316257
AK297409
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 10.1 no CTGgtgagt
S2 5' (donor) 2 10.77 no CAGgtaaga
S3 3' (acceptor) 2 11.59 no ttccccctttttcccaacagAGT
S4 5' (donor) 3 8.08 no CAGgttggt
S5 3' (acceptor) 3 10.7 no gtgattttttccccccccagACC
S6 5' (donor) 4 9.72 no AAAgtaagt
S7 3' (acceptor) 4 4.73 no atggttaaattttttaatagCTC
S8 3' (acceptor) 4 8.88 yes gctctatattctgtctccagGAG
S9 5' (donor) 5 4.75 no GAGgtagca
S10 3' (acceptor) 5 10.57 no tttttatctgttctgaacagGTG
S11 5' (donor) 6 10.13 no ATGgtgagt
S12 3' (acceptor) 6 -0.52 no gaaggagggaacttttccagGTG
S13 5' (donor) 7 8.34 no ACAgtgagt
S14 3' (acceptor) 7 11.2 no tttaatattttctttcctagGTG
S15 5' (donor) 8 9.65 no GGGgtaagt
S16 3' (acceptor) 8 7.46 no actttaatttgtcttactagCGG
S17 5' (donor) 9 8.92 no AAGgtaaca
S18 3' (acceptor) 9 11.56 no tttttttctgtttttaatagGAT
S19 5' (donor) 10 2.48 no TGGgcaagt
S20 3' (acceptor) 10 6.59 no aatggtcacttttattacagAAA
S21 5' (donor) 11 8.17 no CAGgtactt
S22 3' (acceptor) 11 3.85 no gaaaagaattttctcaatagATG
S23 5' (donor) 12 3.26 no CAGgttctt
S24 3' (acceptor) 12 13.06 no atgtcttttctctgttgcagGAC
S25 5' (donor) 13 3.28 no TGGgtaaaa
S26 3' (acceptor) 13 10.99 no tatgaccttttcccctttagGCG
S27 5' (donor) 13 2.99 yes ACAgtgggt
S28 5' (donor) 14 7.61 no CAAgtaaga
S29 3' (acceptor) 14 5.97 no gttttatatctgcttctaagGAA
S30 5' (donor) 15 9.82 no GAAgtaagt
S31 3' (acceptor) 15 8.61 no catcttattttaccttgcagTGA
S32 5' (donor) 16 8.14 no CTGgtatgt
S33 3' (acceptor) 16 7.21 no acttcatgtcccccttcaagATA
S34 5' (donor) 17 11.01 no ATGgtaagt
S35 3' (acceptor) 17 8.53 no ctcccctttccctttcttagCAA
S36 5' (donor) 18 8.07 no CAGgtgggc
S37 3' (acceptor) 18 3.88 no tacgattaaataactgacagATA
S38 5' (donor) 19 8.55 no CAGgtaata
S39 3' (acceptor) 19 8.64 no ttttttcttcctataaacagTTT
S40 3' (acceptor) 20 9.57 no gacatgccttcttttttcagACA
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
19289 2 2
19289 3 3
19289 4 4
19289 6 6
19289 8 8
19289 10 10
19289 11 11
19289 12 12
19289 13 13
19289 14 14
19289 15 15
19289 16 16
19289 17 17
19289 18 18
19289 19 19
19289 20 20
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 4
17 1
18 1
 Transcription termination & last exon(s) 
9 1
15 1
20 1
 Exon skipping 
5 2
 Alternative 3' splice sites 
4 1
 Alternative 5' splice sites 
13 1
 Intron retentions 
17 1
19 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
11 Expression Expression Expression
12 Expression Expression Expression
13 Expression Expression Expression
14 Expression Expression Expression
15 Expression Expression Expression
16 Expression Expression Expression
17 Expression Expression Expression
18 Expression Expression Expression
19 Expression Expression Expression
20 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 355 62502880 - 62503234 355 sequence download
1 Intron 356 - 1830 62503235 - 62504709 1475 sequence -
2 Exon 1831 - 1959 62504710 - 62504838 129 sequence download
2 Intron 1960 - 3411 62504839 - 62506290 1452 sequence -
3 Exon 3412 - 3519 62506291 - 62506398 108 sequence download
3 Intron 3520 - 7467 62506399 - 62510346 3948 sequence -
4 Exon 7468 - 7597 62510347 - 62510476 130 sequence download
4 Intron 7598 - 9961 62510477 - 62512840 2364 sequence -
5 Exon 9962 - 10067 62512841 - 62512946 106 sequence download
5 Intron 10068 - 12559 62512947 - 62515438 2492 sequence -
6 Exon 12560 - 12675 62515439 - 62515554 116 sequence download
6 Intron 12676 - 14640 62515555 - 62517519 1965 sequence -
7 Exon 14641 - 14766 62517520 - 62517645 126 sequence download
7 Intron 14767 - 15940 62517646 - 62518819 1174 sequence -
8 Exon 15941 - 16134 62518820 - 62519013 194 sequence download
8 Intron 16135 - 19008 62519014 - 62521887 2874 sequence -
9 Exon 19009 - 19121 62521888 - 62522000 113 sequence download
9 Intron 19122 - 19309 62522001 - 62522188 188 sequence -
10 Exon 19310 - 19439 62522189 - 62522318 130 sequence download
10 Intron 19440 - 20349 62522319 - 62523228 910 sequence -
11 Exon 20350 - 20503 62523229 - 62523382 154 sequence download
11 Intron 20504 - 22526 62523383 - 62525405 2023 sequence -
12 Exon 22527 - 22666 62525406 - 62525545 140 sequence download
12 Intron 22667 - 24164 62525546 - 62527043 1498 sequence -
13 Exon 24165 - 24261 62527044 - 62527140 97 sequence download
13 Intron 24262 - 25128 62527141 - 62528007 867 sequence -
14 Exon 25129 - 25261 62528008 - 62528140 133 sequence download
14 Intron 25262 - 26077 62528141 - 62528956 816 sequence -
15 Exon 26078 - 26247 62528957 - 62529126 170 sequence download
15 Intron 26248 - 26355 62529127 - 62529234 108 sequence -
16 Exon 26356 - 26430 62529235 - 62529309 75 sequence download
16 Intron 26431 - 27823 62529310 - 62530702 1393 sequence -
17 Exon 27824 - 27976 62530703 - 62530855 153 sequence download
17 Intron 27977 - 29840 62530856 - 62532719 1864 sequence -
18 Exon 29841 - 29987 62532720 - 62532866 147 sequence download
18 Intron 29988 - 30279 62532867 - 62533158 292 sequence -
19 Exon 30280 - 30351 62533159 - 62533230 72 sequence download
19 Intron 30352 - 30841 62533231 - 62533720 490 sequence -
20 Exon 30842 - 31188 62533721 - 62534067 347 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2   UTR 3   UTR 4   UTR 5   UTR 6   UTR 7 
 Supporting GenBank
accession identifers 		 AK316257
 AK290587
 AK057326
BC009518
NM_138363
 AL832822
 AK297409
 BX641136
 BC029461
 Length  106 102 649 524 449 2708 593
 Number of ATGs in frame  0 0 8 7 0 12 1
 Total number of ATGs  0 0 11 11 10 56 8
 Number of GTGs in frame  0 0 4 3 3 18 7
 Total number of GTGs  3 3 14 11 8 67 15
 Number of CTGs in frame  1 1 2 2 2 17 2
 Total number of CTGs  2 3 11 7 6 55 9
 Number of micro ORFs in frame  0 0 3 0 0 5 1
 Total number of micro ORFs  0 0 5 2 1 25 4
 GC percentage  72 72 51 39 43 43 41
 Number of pyrimidine tracks  1 1 4 2 2 14 0
Close 3' untranslated regions 
 UTR 1   UTR 2   UTR 3 
 Supporting GenBank
accession identifers 		 AK057326
AK316257
 BX641136
AK290587
AK297409
BC009518
NM_138363
AL832822
 BC029461
 Length  1240 650 171
 Number of ATGs in frame  16 7 1
 Total number of ATGs  27 20 2
 Number of GTGs in frame  10 4 1
 Total number of GTGs  19 14 2
 Number of CTGs in frame  8 1 1
 Total number of CTGs  11 4 1
 GC percentage  44 39 35
 Number of pyrimidine tracks  6 4 1
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-425 1850 - 1872 62504729 - 62504751 miranda
M2 hsa-miR-150 1927 - 1948 62504806 - 62504827 miranda
Group 2
M1 hsa-miR-149 9994 - 10019 62512873 - 62512898 miranda
Group 3
M1 hsa-miR-485-5p 19311 - 19334 62522190 - 62522213 miranda
M2 hsa-miR-216b 19355 - 19376 62522234 - 62522255 miranda
M3 hsa-miR-375 19364 - 19386 62522243 - 62522265 miranda
Group 4
M1 hsa-miR-204 24170 - 24191 62527049 - 62527070 miranda
M2 hsa-miR-211 24170 - 24191 62527049 - 62527070 miranda
Group 5
M1 hsa-miR-876-5p 26218 - 26240 62529097 - 62529119 miranda
Group 6
M1 hsa-miR-149 31019 - 31026 62533898 - 62533905 pictar
M2 hsa-miR-149 31067 - 31088 62533946 - 62533967 miranda
M3 hsa-miR-149 31070 - 31077 62533949 - 62533956 pictar
M4 hsa-miR-149 31082 - 31089 62533961 - 62533968 pictar
M5 hsa-miR-149 31099 - 31106 62533978 - 62533985 pictar
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Binding EXONT:002965 Calponin homology domain 2,3,4 1848 7533
Localization EXONT:000064 Nuclear_localization_signal 11 20488 20499
Localization EXONT:000064 Nuclear_localization_signal 12 22538 22555
Localization EXONT:000064 Nuclear_localization_signal 12 22616 22627
Localization EXONT:000064 Nuclear_localization_signal 15 26197 26241
Localization EXONT:000065 Endosomal_localization_signal 20 30929 30961
Localization EXONT:000066 Lysosomal_localization_signal 20 30929 30961
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 4,5 7591 10053
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 6 12579 12635
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 7 14661 14741
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 8 15958 15978
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 8 15982 15999
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 8 16027 16059
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 8 16102 16131
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 9,10 19060 19418
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 11,12 20353 22651
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 13,14 24207 25158
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 14 25204 25254
Structure EXONT:000035 Coiled_coil 15,16 26158 26409
Structure EXONT:000035 Coiled_coil 18,19,20 29868 30934
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 18 29907 29960
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 19,20 30319 30862
PTM EXONT:000161 O-phospho-L-serine 4,5 7597 9963
PTM EXONT:000797 Ubiquitinylated lysine 5 10027 10029
PTM EXONT:000797 Ubiquitinylated lysine 9 19057 19059
PTM EXONT:000162 O-phospho-L-threonine 9 19096 19098
PTM EXONT:000238 Dimethylated L-arginine 9,10 19120 19310
PTM EXONT:000161 O-phospho-L-serine 10 19344 19346
PTM EXONT:000797 Ubiquitinylated lysine 10 19407 19409
PTM EXONT:000797 Ubiquitinylated lysine 11 20356 20358
PTM EXONT:000161 O-phospho-L-serine 11 20452 20454
PTM EXONT:000161 O-phospho-L-serine 11 20461 20463
PTM EXONT:000161 O-phospho-L-serine 12 22559 22561
PTM EXONT:000161 O-phospho-L-serine 12 22565 22567
PTM EXONT:000161 O-phospho-L-serine 12 22571 22573
PTM EXONT:000161 O-phospho-L-serine 12 22577 22579
PTM EXONT:000162 O-phospho-L-threonine 14 25210 25215
PTM EXONT:000797 Ubiquitinylated lysine 15 26197 26199
PTM EXONT:000164 O4'-phospho-L-tyrosine 17 27911 27916
PTM EXONT:000164 O4'-phospho-L-tyrosine 17 27923 27925
PTM EXONT:000797 Ubiquitinylated lysine 18 29880 29882
PTM EXONT:000164 O4'-phospho-L-tyrosine 18 29973 29978
PTM EXONT:000797 Ubiquitinylated lysine 19 30325 30327
PTM EXONT:000161 O-phospho-L-serine 20 31004 31006
Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45
Gene CCDC45 Gene CCDC45

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 20Extended region