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Previous gene FasterDB identifier: 17164 - POLG2 (HP55, MTPOLB) polymerase (DNA directed), gamma 2, accessory subunit Next gene
Gene Close
Symbol POLG2
Synonyms HP55, MTPOLB
Description polymerase (DNA directed), gamma 2, accessory subunit
EnsEMBL link ENSG00000136480
Chromosome 17 - reverse strand
Chromosomal location
(UCSC link)		 62473902 - 62493184 (19283bp)
Sequence sequence
Associated transcripts NM_007215 BC009194 U94703 AF184344 AF142992 AK307801 AF177201 BC000913 CR617858
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 62493184 NM_007215
P2 1 48 62493137 AK307801
Protein prediction Close
 Transcript name   Sequence 
NM_007215 sequence
BC009194 sequence
U94703 sequence
AF184344 sequence
AF142992 sequence
AK307801 sequence
AF177201 sequence
BC000913 sequence
CR617858 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 5 11474 62481711 no AK307801 Full_length
PA2 8 19283 62473902 AATAAA no CR617858 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
No data
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 8.56 no ACGgtatgc
S2 5' (donor) 2 7.08 no AAGgtataa
S3 3' (acceptor) 2 8.04 no attgatttatcttttgacagGTG
S4 5' (donor) 3 8.56 no AAGgtactg
S5 3' (acceptor) 3 2.11 no gatacgttttatatctaaagTAT
S6 5' (donor) 4 5.71 no CATgtatgt
S7 3' (acceptor) 4 9.82 no acttaaattttcttttccagTTT
S8 5' (donor) 5 4.05 no AAGgtgctg
S9 3' (acceptor) 5 8.14 no tcttctgtttttctgtgaagGGC
S10 5' (donor) 6 10.67 no CAGgtgagt
S11 3' (acceptor) 6 8.42 no cccccatttaattgccttagGTA
S12 5' (donor) 7 6.42 no GAAgtaaga
S13 3' (acceptor) 7 11.81 no gtttttctatttctttctagGTT
S14 3' (acceptor) 8 8.75 no tttaactacttttttcttagGTA
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
19190 1 1
19190 2 2
19190 3 3
19190 4 4
19190 5 5
19190 6 6
19190 7 7
19190 8 9
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 2
 Transcription termination & last exon(s) 
5 1
8 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 660 62492525-62493184 660 sequence download
1 Intron 661 - 4046 62489139-62492524 3386 sequence -
2 Exon 4047 - 4173 62489012-62489138 127 sequence download
2 Intron 4174 - 4295 62488890-62489011 122 sequence -
3 Exon 4296 - 4401 62488784-62488889 106 sequence download
3 Intron 4402 - 6098 62487087-62488783 1697 sequence -
4 Exon 6099 - 6272 62486913-62487086 174 sequence download
4 Intron 6273 - 11199 62481986-62486912 4927 sequence -
5 Exon 11200 - 11340 62481845-62481985 141 sequence download
5 Intron 11341 - 14068 62479117-62481844 2728 sequence -
6 Exon 14069 - 14149 62479036-62479116 81 sequence download
6 Intron 14150 - 16678 62476507-62479035 2529 sequence -
7 Exon 16679 - 16779 62476406-62476506 101 sequence download
7 Intron 16780 - 19079 62474106-62476405 2300 sequence -
8 Exon 19080 - 19283 62473902-62474105 204 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2   UTR 3   UTR 4   UTR 5 
 Supporting GenBank
accession identifers 		 NM_007215
BC009194
 AK307801
 U94703
AF184344
AF142992
 BC000913
 CR617858
 Length  98 51 402 647 183
 Number of ATGs in frame  1 1 2 0 0
 Total number of ATGs  1 1 4 5 3
 Number of GTGs in frame  1 0 2 6 0
 Total number of GTGs  2 0 10 13 2
 Number of CTGs in frame  1 1 2 5 1
 Total number of CTGs  5 2 8 16 1
 Number of micro ORFs in frame  1 1 0 0 0
 Total number of micro ORFs  1 1 2 4 3
 GC percentage  56 51 60 51 39
 Number of pyrimidine tracks  0 0 0 3 1
Close 3' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 		 AK307801
 CR617858
NM_007215
BC009194
U94703
AF184344
AF142992
BC000913
 Length  371 38
 Number of ATGs in frame  3 0
 Total number of ATGs  11 0
 Number of GTGs in frame  4 0
 Total number of GTGs  7 0
 Number of CTGs in frame  4 0
 Total number of CTGs  7 0
 GC percentage  38 16
 Number of pyrimidine tracks  1 1
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-185 19260 - 19281 62473904 - 62473925 miranda
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Binding EXONT:001885 Protein binding 1,2,3,4,5,6,7,8 99 19242
Binding EXONT:004898 Identical protein binding 1 537 632
Localization EXONT:000069 ER_retention_signal 1 99 113
Localization EXONT:000064 Nuclear_localization_signal 2 4088 4102
Localization EXONT:000067 Nuclear_export_signal 8 19084 19122
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 1 180 299
Structure EXONT:000037 Peptide_helix 1 303 323
Structure EXONT:000051 Beta_strand 1 330 338
Structure EXONT:000022 Polypeptide_turn_motif 1 345 356
Structure EXONT:000037 Peptide_helix 1 360 374
Structure EXONT:000037 Peptide_helix 1 399 452
Structure EXONT:000022 Polypeptide_turn_motif 1 453 464
Structure EXONT:000051 Beta_strand 1 471 479
Structure EXONT:000051 Beta_strand 1 492 500
Structure EXONT:000022 Polypeptide_turn_motif 1 501 509
Structure EXONT:000051 Beta_strand 1 534 545
Structure EXONT:000037 Peptide_helix 1 546 566
Structure EXONT:000051 Beta_strand 1 567 575
Structure EXONT:000022 Polypeptide_turn_motif 1 579 593
Structure EXONT:000037 Peptide_helix 1 594 602
Structure EXONT:000037 Peptide_helix 1 609 629
Structure EXONT:000051 Beta_strand 1 633 641
Structure EXONT:000037 Peptide_helix 1,2 654 4060
Structure EXONT:000022 Polypeptide_turn_motif 2 4061 4075
Structure EXONT:000037 Peptide_helix 2 4076 4084
Structure EXONT:000051 Beta_strand 2 4091 4129
Structure EXONT:000051 Beta_strand 3 4303 4335
Structure EXONT:000037 Peptide_helix 3,4 4339 6101
Structure EXONT:000037 Peptide_helix 4 6111 6119
Structure EXONT:000051 Beta_strand 4 6120 6137
Structure EXONT:000051 Beta_strand 4 6144 6155
Structure EXONT:000051 Beta_strand 4 6159 6179
Structure EXONT:000051 Beta_strand 4 6192 6218
Structure EXONT:000037 Peptide_helix 4 6228 6245
Structure EXONT:000051 Beta_strand 4 6258 6269
Structure EXONT:000051 Beta_strand 5 11203 11214
Structure EXONT:000051 Beta_strand 5 11230 11253
Structure EXONT:000037 Peptide_helix 5 11254 11283
Structure EXONT:000022 Polypeptide_turn_motif 6 14084 14092
Structure EXONT:000051 Beta_strand 6 14093 14101
Structure EXONT:000051 Beta_strand 6 14105 14125
Structure EXONT:000037 Peptide_helix 6,7 14141 16711
Structure EXONT:000051 Beta_strand 7 16724 16732
Structure EXONT:000037 Peptide_helix 7 16733 16741
Structure EXONT:000051 Beta_strand 7 16742 16750
Structure EXONT:000037 Peptide_helix 7,8 16763 19092
Structure EXONT:000051 Beta_strand 8 19099 19116
Structure EXONT:000037 Peptide_helix 8 19120 19131
Structure EXONT:000051 Beta_strand 8 19135 19158
Structure EXONT:000022 Polypeptide_turn_motif 8 19159 19167
Structure EXONT:000051 Beta_strand 8 19177 19188
Structure EXONT:000037 Peptide_helix 8 19195 19239
PTM EXONT:000180 N-acetylated L-lysine 4 6165 6167
PTM EXONT:000192 N6-acetyl-L-lysine 4 6165 6167
PTM EXONT:000162 O-phospho-L-threonine 5 11299 11301
PTM EXONT:000162 O-phospho-L-threonine 5 11314 11316
Unclassified EXONT:003919 Anticodon-binding 5,6,7,8 11335 19239
Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2
Gene POLG2 Gene POLG2

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Extended region