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Previous gene FasterDB identifier: 2289 - DMC1 (LIM15) DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) Next gene
Gene Close
Symbol DMC1
Synonyms LIM15
Description DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
EnsEMBL link ENSG00000100206
Chromosome 22 - reverse strand
Chromosomal location
(UCSC link)		 38914954 - 38966201 (51248bp)
Sequence sequence
Associated transcripts AK292617 BC035658 NM_007068 BC125164 BC125163 D63882 CR456486 D64108 AK297664
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 8 -582 AK292617
NM_007068
BC125164
BC125163
D63882
CR456486
D64108
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 38966201 AK292617
P2 2 1788 38964414 AK297664
Protein prediction Close
 Transcript name   Sequence 
AK292617 sequence
BC035658 sequence
NM_007068 sequence
BC125164 sequence
BC125163 sequence
D63882 sequence
CR456486 sequence
D64108 sequence
AK297664 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 9 24429 38941773 AATAAA yes BC035658 Cdna
PA2 15 50222 38915980 no AK297664 Full_length
PA3 15 51117 38915085 no AK292617 Full_length
PA4 15 51248 38914954 AATAAA no NM_007068 Cdna
PA5 15 51248 38914954 AATAAA no D64108 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
ES1 8 AK297664
ES2 9 AK292617
NM_007068
BC125164
BC125163
D63882
CR456486
D64108
AK297664
ES3 10 AK297664
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 9.65 no GGGgtaagt
S2 5' (donor) 2 8.55 no GAGgtatga
S3 3' (acceptor) 2 6.45 no aatatttcttattttcccagAAG
S4 5' (donor) 3 8.54 no ATTgtaagt
S5 3' (acceptor) 3 10.87 no ttctgtttcatctcctttagGAA
S6 5' (donor) 4 5.06 no ATTgtaagc
S7 3' (acceptor) 4 8.62 no gcccattctttaatttacagAAC
S8 5' (donor) 5 4.43 no TGAgtatgt
S9 3' (acceptor) 5 11.2 no ttccttttatctttctgtagGAA
S10 5' (donor) 6 9.65 no GAGgtaggt
S11 3' (acceptor) 6 8.9 no tgctttctttctatttccagTAA
S12 5' (donor) 7 8.37 no GTGgtaagg
S13 3' (acceptor) 7 11.15 no tttttttctgtatttcacagAAT
S14 5' (donor) 8 -13.49 no CTGgctgaa
S15 3' (acceptor) 8 4.95 no aatttttaattgcttcctagTGA
S16 5' (donor) 8 -1.98 yes TTTgtaacc
S17 5' (donor) 9 -22.95 no CTGaacttc
S18 3' (acceptor) 9 -10.25 no ggcgtgagccacgatgcccgGCC
S19 5' (donor) 10 5.2 no CTAgtaaga
S20 3' (acceptor) 10 3.04 no ttaatcttggcatactccagCCG
S21 5' (donor) 11 -0.43 no TTGgtacaa
S22 3' (acceptor) 11 8.94 no ctcactgcatttcccatcagGTG
S23 5' (donor) 12 7.84 no AAGgtatat
S24 3' (acceptor) 12 6.66 no tttacattaatcctgtgtagATT
S25 5' (donor) 13 7.1 no GACgtaagc
S26 3' (acceptor) 13 6.78 no aattttatctcttgatgcagAAT
S27 5' (donor) 14 8.76 no CAGgtaaat
S28 3' (acceptor) 14 2.4 no agagtattttattaattcagCTT
S29 3' (acceptor) 15 4.76 no gttcccttgtattctgttagTCC
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
16790 1 1
16790 2 2
16790 3 3
16790 4 4
16790 5 5
16790 6 6
16790 7 7
16790 8 8
16790 10 9
16790 11 10
16790 12 11
16790 13 12
16790 14 13
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 1
2 1
 Transcription termination & last exon(s) 
9 1
15 4
 Exon skipping 
8 1
9 8
10 1
 Alternative 5' splice sites 
8 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
11 Expression Expression Expression
12 Expression Expression Expression
13 Expression Expression Expression
14 Expression Expression Expression
15 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 154 38966048-38966201 154 sequence download
1 Intron 155 - 1907 38964295-38966047 1753 sequence -
2 Exon 1908 - 1991 38964211-38964294 84 sequence download
2 Intron 1992 - 2569 38963633-38964210 578 sequence -
3 Exon 2570 - 2614 38963588-38963632 45 sequence download
3 Intron 2615 - 3460 38962742-38963587 846 sequence -
4 Exon 3461 - 3607 38962595-38962741 147 sequence download
4 Intron 3608 - 7827 38958375-38962594 4220 sequence -
5 Exon 7828 - 7910 38958292-38958374 83 sequence download
5 Intron 7911 - 14787 38951415-38958291 6877 sequence -
6 Exon 14788 - 14840 38951362-38951414 53 sequence download
6 Intron 14841 - 17489 38948713-38951361 2649 sequence -
7 Exon 17490 - 17531 38948671-38948712 42 sequence download
7 Intron 17532 - 20199 38946003-38948670 2668 sequence -
8 Exon 20200 - 20854 38945348-38946002 655 sequence download
8 Intron 20855 - 24085 38942117-38945347 3231 sequence -
9 Exon 24086 - 24429 38941773-38942116 344 sequence download
9 Intron 24430 - 30784 38935418-38941772 6355 sequence -
10 Exon 30785 - 30876 38935326-38935417 92 sequence download
10 Intron 30877 - 31584 38934618-38935325 708 sequence -
11 Exon 31585 - 31658 38934544-38934617 74 sequence download
11 Intron 31659 - 31787 38934415-38934543 129 sequence -
12 Exon 31788 - 31902 38934300-38934414 115 sequence download
12 Intron 31903 - 32544 38933658-38934299 642 sequence -
13 Exon 32545 - 32605 38933597-38933657 61 sequence download
13 Intron 32606 - 48472 38917730-38933596 15867 sequence -
14 Exon 48473 - 48589 38917613-38917729 117 sequence download
14 Intron 48590 - 50107 38916095-38917612 1518 sequence -
15 Exon 50108 - 51248 38914954-38916094 1141 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 		 AK292617
BC035658
NM_007068
BC125164
BC125163
D63882
CR456486
D64108
 AK297664
 Length  187 585
 Number of ATGs in frame  0 5
 Total number of ATGs  0 10
 Number of GTGs in frame  1 4
 Total number of GTGs  5 10
 Number of CTGs in frame  1 2
 Total number of CTGs  4 7
 Number of micro ORFs in frame  0 2
 Total number of micro ORFs  0 4
 GC percentage  58 39
 Number of pyrimidine tracks  2 5
Close 3' untranslated regions 
 UTR 1   UTR 2   UTR 3 
 Supporting GenBank
accession identifers 		 BC035658
 D64108
AK292617
D63882
BC125163
BC125164
AK297664
CR456486
 NM_007068
 Length  922 1074 1071
 Number of ATGs in frame  4 8 8
 Total number of ATGs  15 22 22
 Number of GTGs in frame  7 6 6
 Total number of GTGs  19 14 14
 Number of CTGs in frame  4 9 11
 Total number of CTGs  15 22 22
 GC percentage  40 36 36
 Number of pyrimidine tracks  9 7 7
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-543 20303 - 20324 38945878 - 38945899 miranda
M2 hsa-miR-7 20347 - 20370 38945832 - 38945855 miranda
M3 hsa-miR-9 20376 - 20400 38945802 - 38945826 miranda
M4 hsa-miR-204 20380 - 20403 38945799 - 38945822 miranda
M5 hsa-miR-211 20382 - 20403 38945799 - 38945820 miranda
M6 hsa-miR-146b-5p 20405 - 20426 38945776 - 38945797 miranda
M7 hsa-miR-146a 20405 - 20426 38945776 - 38945797 miranda
M8 hsa-miR-339-5p 20727 - 20751 38945451 - 38945475 miranda
Group 2
M1 hsa-miR-197 50178 - 50185 38916017 - 38916024 targetscan
M2 hsa-miR-197 50178 - 50185 38916017 - 38916024 miranda
Group 3
M1 hsa-miR-299-3p 50262 - 50281 38915921 - 38915940 miranda
M2 hsa-miR-548d-3p 50266 - 50272 38915930 - 38915936 pita
M3 hsa-miR-802 50280 - 50286 38915916 - 38915922 pita
M4 hsa-miR-216b 50287 - 50310 38915892 - 38915915 miranda
M5 hsa-miR-628-5p 50295 - 50301 38915901 - 38915907 pita
M6 hsa-miR-216b 50303 - 50309 38915893 - 38915899 pita
M7 hsa-miR-539 50442 - 50464 38915738 - 38915760 miranda
M8 hsa-miR-654-3p 50761 - 50767 38915435 - 38915441 pita
M9 hsa-miR-186 50797 - 50820 38915382 - 38915405 miranda
M10 hsa-miR-548i 50812 - 50819 38915383 - 38915390 pita
M11 hsa-miR-548b-5p 50812 - 50819 38915383 - 38915390 pita
M12 hsa-miR-548j 50812 - 50819 38915383 - 38915390 pita
M13 hsa-miR-548c-5p 50812 - 50819 38915383 - 38915390 pita
M14 hsa-miR-548d-5p 50812 - 50819 38915383 - 38915390 pita
M15 hsa-miR-548h 50812 - 50819 38915383 - 38915390 pita
M16 hsa-miR-548a-5p 50812 - 50819 38915383 - 38915390 pita
M17 hsa-miR-548n 50813 - 50820 38915382 - 38915389 pita
M18 hsa-miR-559 50813 - 50819 38915383 - 38915389 pita
Group 4
M1 hsa-miR-590-3p 51134 - 51155 38915047 - 38915068 miranda
M2 hsa-miR-590-3p 51148 - 51155 38915047 - 38915054 targetscan
M3 hsa-miR-590-3p 51152 - 51172 38915030 - 38915050 miranda
M4 hsa-miR-1290 51228 - 51234 38914968 - 38914974 pita
M5 hsa-miR-570 51234 - 51241 38914961 - 38914968 pita
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Catalytic EXONT:009027 DNA recombination/repair protein RecA-like, ATP-binding domain 5,6,7,8,10,11,12,13 7873 32591
Catalytic EXONT:009026 DNA recombination/repair protein RecA, monomer-monomer interface 13,14,15 32598 50174
Binding EXONT:005892 DNA repair Rad51/transcription factor NusA, alpha-helical 2,3,4 1986 3607
Binding EXONT:009027 DNA recombination/repair protein RecA-like, ATP-binding domain 5,6,7,8,10,11,12,13 7873 32591
Binding EXONT:000062 Nucleotide_binding_site 6,7 14837 17509
Binding EXONT:009026 DNA recombination/repair protein RecA, monomer-monomer interface 13,14,15 32598 50174
Localization EXONT:000064 Nuclear_localization_signal 4 3476 3487
Localization EXONT:000067 Nuclear_export_signal 10 30792 30836
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 2 1941 1982
Structure EXONT:000051 Beta_strand 5 7837 7845
Structure EXONT:000037 Peptide_helix 5 7846 7869
Structure EXONT:000037 Peptide_helix 5,6 7900 14794
Structure EXONT:000051 Beta_strand 6 14801 14815
Structure EXONT:000051 Beta_strand 6,7 14819 17491
Structure EXONT:000037 Peptide_helix 7,8 17504 20204
Structure EXONT:000037 Peptide_helix 8 20220 20228
Structure EXONT:000051 Beta_strand 8 20241 20267
Structure EXONT:000037 Peptide_helix 10 30789 30821
Structure EXONT:000037 Peptide_helix 10 30831 30848
Structure EXONT:000051 Beta_strand 10 30852 30866
Structure EXONT:000037 Peptide_helix 10,11 30876 31634
Structure EXONT:000051 Beta_strand 11,12 31644 31796
Structure EXONT:000037 Peptide_helix 12 31806 31823
Structure EXONT:000037 Peptide_helix 12 31830 31838
Structure EXONT:000037 Peptide_helix 12,13 31842 32546
Structure EXONT:000051 Beta_strand 13 32556 32573
Structure EXONT:000051 Beta_strand 14 48495 48503
Structure EXONT:000037 Peptide_helix 14 48504 48524
Structure EXONT:000051 Beta_strand 14 48528 48551
Structure EXONT:000051 Beta_strand 14 48564 48587
Structure EXONT:000037 Peptide_helix 15 50118 50126
Structure EXONT:000051 Beta_strand 15 50127 50147
Structure EXONT:000051 Beta_strand 15 50154 50165
Unclassified EXONT:002271 P-loop containing nucleoside triphosphate hydrolase 4,5,6,7,8,10,11,12,13,14,15 3545 50165
Unclassified EXONT:006814 DNA recombination and repair protein Rad51, C-terminal 5,6,7,8,10,11,12,13,14,15 7834 50171
Unclassified EXONT:002272 AAA+ ATPase domain 6,7,8,10,11,12,13,14 14813 48557
Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1
Gene DMC1 Gene DMC1

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Extended region