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Previous gene FasterDB identifier: 11765 - MCM10 (CNA43, DNA43, PRO2249) minichromosome maintenance complex component 10 Next gene
Gene Close
Symbol MCM10
Synonyms CNA43, DNA43, PRO2249
Description minichromosome maintenance complex component 10
EnsEMBL link ENSG00000065328
Chromosome 10 - forward strand
Chromosomal location
(UCSC link)		 13203554 - 13253095 (49542bp)
Sequence sequence
Associated transcripts NM_018518 NM_182751 AK292701 AK055695 BC101727 AB042719 AL136840 BC143490 BC009108 BC004876 AF119869 CR620605
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 5 3 NM_018518
AB042719
AL136840
BC143490
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
Intron retentions Close
 Identifier   Position   Transcript 
IR1 19 AL136840
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 13203554 NM_018518
NM_182751
P2 1 26 13203579 AK292701
P3 1 28 13203581 AK055695
Protein prediction Close
 Transcript name   Sequence 
NM_018518 sequence
NM_182751 sequence
AK292701 sequence
AK055695 sequence
BC101727 sequence
AB042719 sequence
AL136840 sequence
BC143490 sequence
BC009108 sequence
BC004876 sequence
AF119869 sequence
CR620605 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 15 36132 13239685 no AK055695 Full_length
PA2 20 48183 13251736 no AK292701 Full_length
PA3 20 48345 13251898 ATTAAA no AA583783 3prime_est
PA4 20 49542 13253095 yes NM_018518 Cdna
PA5 20 49542 13253095 yes NM_182751 Cdna
PA6 20 49542 13253095 yes AL136840 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
No data
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 8.48 no CGGgtgagg
S2 5' (donor) 2 9.48 no ATGgtaaga
S3 3' (acceptor) 2 6.35 no ctaatattgctttcacacagCCA
S4 5' (donor) 3 5.96 no AAGgtgccc
S5 3' (acceptor) 3 11.72 no tttctcttcttttcccctagAGG
S6 5' (donor) 4 9.45 no CTGgtaaga
S7 3' (acceptor) 4 7.17 no aacatattttcatttcctagAGG
S8 5' (donor) 5 3.1 no CAGgtgtag
S9 3' (acceptor) 5 1.31 no ttattttacttttgattaagTAG
S10 5' (donor) 6 8.94 no CAGgtcagt
S11 3' (acceptor) 6 7.74 no taattgtgttaattttctagATC
S12 5' (donor) 7 5.32 no AGTgtaagc
S13 3' (acceptor) 7 4.72 no tcgctggtttcttaacccagGCG
S14 5' (donor) 8 10.06 no GAGgtaaga
S15 3' (acceptor) 8 5.49 no aaaataactatttgttccagGGA
S16 5' (donor) 9 2.01 no TTGgttggt
S17 3' (acceptor) 9 11.39 no tgccccaccttttcttacagGTG
S18 5' (donor) 10 5.55 no AATgtaaga
S19 3' (acceptor) 10 10.11 no cactgctctgccttttgcagCGT
S20 5' (donor) 11 6.25 no TCGgtaact
S21 3' (acceptor) 11 5.29 no ggggtgacttgtcatttcagTGC
S22 5' (donor) 12 7.88 no CAGgtacca
S23 3' (acceptor) 12 3.35 no ctggtgttgacctggcacagGAA
S24 5' (donor) 13 9.63 no GCGgtaaga
S25 3' (acceptor) 13 8.21 no agtctgggcttctgtttcagGGA
S26 5' (donor) 14 9.01 no AAGgtaact
S27 3' (acceptor) 14 6.9 no tgactgtatgttctttaaagATT
S28 5' (donor) 15 8.56 no AAGgtactg
S29 3' (acceptor) 15 8.22 no tctcattcccttttttctagTTA
S30 5' (donor) 16 10.06 no GAGgtaaga
S31 3' (acceptor) 16 6.83 no gtttgttccttgtgccctagCTG
S32 5' (donor) 17 8.27 no ACGgtgggt
S33 3' (acceptor) 17 7.58 no attatgccctgtcattccagGCC
S34 5' (donor) 18 9.46 no CAGgtatga
S35 3' (acceptor) 18 8.45 no ttttttgttgctctgtgcagTGC
S36 5' (donor) 19 9.55 no AAGgtatgc
S37 3' (acceptor) 19 8.63 no atccatctgttctgtttcagTAA
S38 3' (acceptor) 20 8.98 no aaatattttcatttttctagGAA
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
9390 3 4
9390 4 5
9390 5 6
9390 6 7
9390 7 8
9390 8 9
9390 9 10
9390 10 11
9390 11 12
9390 12 13
9390 13 14
9390 14 15
9390 15 16
9390 16 17
9390 17 18
9390 18 19
9390 19 20
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 3
 Transcription termination & last exon(s) 
15 1
20 5
 Alternative 3' splice sites 
5 1
 Intron retentions 
19 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
11 Expression Expression Expression
12 Expression Expression Expression
13 Expression Expression Expression
14 Expression Expression Expression
15 Expression Expression Expression
16 Expression Expression Expression
17 Expression Expression Expression
18 Expression Expression Expression
19 Expression Expression Expression
20 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 53 13203554 - 13203606 53 sequence download
1 Intron 54 - 2574 13203607 - 13206127 2521 sequence -
2 Exon 2575 - 2656 13206128 - 13206209 82 sequence download
2 Intron 2657 - 9368 13206210 - 13212921 6712 sequence -
3 Exon 9369 - 9710 13212922 - 13213263 342 sequence download
3 Intron 9711 - 10822 13213264 - 13214375 1112 sequence -
4 Exon 10823 - 10927 13214376 - 13214480 105 sequence download
4 Intron 10928 - 11071 13214481 - 13214624 144 sequence -
5 Exon 11072 - 11212 13214625 - 13214765 141 sequence download
5 Intron 11213 - 13956 13214766 - 13217509 2744 sequence -
6 Exon 13957 - 14128 13217510 - 13217681 172 sequence download
6 Intron 14129 - 18888 13217682 - 13222441 4760 sequence -
7 Exon 18889 - 19054 13222442 - 13222607 166 sequence download
7 Intron 19055 - 21379 13222608 - 13224932 2325 sequence -
8 Exon 21380 - 21547 13224933 - 13225100 168 sequence download
8 Intron 21548 - 24610 13225101 - 13228163 3063 sequence -
9 Exon 24611 - 24727 13228164 - 13228280 117 sequence download
9 Intron 24728 - 27327 13228281 - 13230880 2600 sequence -
10 Exon 27328 - 27527 13230881 - 13231080 200 sequence download
10 Intron 27528 - 29745 13231081 - 13233298 2218 sequence -
11 Exon 29746 - 29846 13233299 - 13233399 101 sequence download
11 Intron 29847 - 30701 13233400 - 13234254 855 sequence -
12 Exon 30702 - 30812 13234255 - 13234365 111 sequence download
12 Intron 30813 - 30897 13234366 - 13234450 85 sequence -
13 Exon 30898 - 31015 13234451 - 13234568 118 sequence download
13 Intron 31016 - 33487 13234569 - 13237040 2472 sequence -
14 Exon 33488 - 33716 13237041 - 13237269 229 sequence download
14 Intron 33717 - 36069 13237270 - 13239622 2353 sequence -
15 Exon 36070 - 36214 13239623 - 13239767 145 sequence download
15 Intron 36215 - 37135 13239768 - 13240688 921 sequence -
16 Exon 37136 - 37254 13240689 - 13240807 119 sequence download
16 Intron 37255 - 39867 13240808 - 13243420 2613 sequence -
17 Exon 39868 - 39981 13243421 - 13243534 114 sequence download
17 Intron 39982 - 42665 13243535 - 13246218 2684 sequence -
18 Exon 42666 - 42811 13246219 - 13246364 146 sequence download
18 Intron 42812 - 47537 13246365 - 13251090 4726 sequence -
19 Exon 47538 - 47580 13251091 - 13251133 43 sequence download
19 Intron 47581 - 47673 13251134 - 13251226 93 sequence -
20 Exon 47674 - 49542 13251227 - 13253095 1869 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2   UTR 3 
 Supporting GenBank
accession identifers 		 NM_018518
NM_182751
BC101727
AB042719
AL136840
BC143490
 AK292701
 AF119869
 Length  128 103 27
 Number of ATGs in frame  0 0 0
 Total number of ATGs  0 0 0
 Number of GTGs in frame  2 1 1
 Total number of GTGs  5 4 2
 Number of CTGs in frame  0 0 0
 Total number of CTGs  1 1 0
 Number of micro ORFs in frame  0 0 0
 Total number of micro ORFs  0 0 0
 GC percentage  53 53 52
 Number of pyrimidine tracks  1 1 0
Close 3' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 		 AL136840
BC009108
AB042719
BC004876
AF119869
AK292701
BC101727
BC143490
 NM_018518
NM_182751
 Length  1936 1785
 Number of ATGs in frame  10 12
 Total number of ATGs  31 28
 Number of GTGs in frame  16 15
 Total number of GTGs  39 35
 Number of CTGs in frame  10 5
 Total number of CTGs  24 23
 GC percentage  36 36
 Number of pyrimidine tracks  17 17
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-384 47658 - 47677 13251211 - 13251230 miranda
Group 2
M1 hsa-miR-194 47693 - 47714 13251246 - 13251267 miranda
Group 3
M1 hsa-miR-339-5p 48506 - 48528 13252059 - 13252081 miranda
M2 hsa-miR-590-3p 49037 - 49056 13252590 - 13252609 miranda
M3 hsa-miR-340 49155 - 49178 13252708 - 13252731 miranda
M4 hsa-miR-653 49190 - 49211 13252743 - 13252764 miranda
M5 hsa-miR-373 49231 - 49255 13252784 - 13252808 miranda
M6 hsa-miR-372 49233 - 49255 13252786 - 13252808 miranda
M7 hsa-miR-520e 49233 - 49255 13252786 - 13252808 miranda
M8 hsa-miR-302a 49233 - 49255 13252786 - 13252808 miranda
M9 hsa-miR-302b 49233 - 49255 13252786 - 13252808 miranda
M10 hsa-miR-302d 49233 - 49255 13252786 - 13252808 miranda
M11 hsa-miR-302c 49234 - 49255 13252787 - 13252808 miranda
M12 hsa-miR-520c-3p 49234 - 49255 13252787 - 13252808 miranda
M13 hsa-miR-520b 49235 - 49255 13252788 - 13252808 miranda
M14 hsa-miR-520a-3p 49237 - 49255 13252790 - 13252808 miranda
M15 hsa-miR-520d-3p 49237 - 49255 13252790 - 13252808 miranda
M16 hsa-miR-302e 49240 - 49255 13252793 - 13252808 miranda
M17 hsa-miR-410 49437 - 49456 13252990 - 13253009 miranda
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Binding EXONT:001885 Protein binding 12,13,14,15,16,17,18,19,20 30749 47754
Localization EXONT:000017 Cilia targeting sequence 3 9656 9670
Localization EXONT:000065 Endosomal_localization_signal 6,7 14103 18892
Localization EXONT:000066 Lysosomal_localization_signal 6,7 14103 18892
Localization EXONT:000064 Nuclear_localization_signal 10 27385 27435
Localization EXONT:000064 Nuclear_localization_signal 15 36139 36150
Localization EXONT:000064 Nuclear_localization_signal 16 37156 37173
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 2,3,4 2650 10857
Structure EXONT:000035 Coiled_coil 3,4 9671 10899
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 4,5,6 10867 14096
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 7 18893 18922
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 12,13 30797 30947
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 13,14 30957 33632
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 14 33639 33698
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 15,16 36097 37170
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 20 47683 47703
PTM EXONT:000162 O-phospho-L-threonine 3 9614 9616
PTM EXONT:000161 O-phospho-L-serine 3 9638 9640
PTM EXONT:000161 O-phospho-L-serine 3 9644 9646
PTM EXONT:000161 O-phospho-L-serine 4 10921 10923
PTM EXONT:000161 O-phospho-L-serine 5 11080 11082
PTM EXONT:000161 O-phospho-L-serine 5 11203 11205
PTM EXONT:000161 O-phospho-L-serine 6 13995 13997
PTM EXONT:000162 O-phospho-L-threonine 6 14010 14012
PTM EXONT:000161 O-phospho-L-serine 6 14016 14018
PTM EXONT:000161 O-phospho-L-serine 7 18902 18904
PTM EXONT:000162 O-phospho-L-threonine 7 19007 19009
PTM EXONT:000164 O4'-phospho-L-tyrosine 10 27487 27489
PTM EXONT:000161 O-phospho-L-serine 10 27523 27525
PTM EXONT:000797 Ubiquitinylated lysine 11 29804 29806
PTM EXONT:000162 O-phospho-L-threonine 12 30803 30805
PTM EXONT:000161 O-phospho-L-serine 13 30909 30911
PTM EXONT:000161 O-phospho-L-serine 13 30936 30938
PTM EXONT:000162 O-phospho-L-threonine 14 33567 33569
PTM EXONT:000161 O-phospho-L-serine 14 33573 33575
PTM EXONT:000162 O-phospho-L-threonine 14 33612 33614
PTM EXONT:000797 Ubiquitinylated lysine 14 33618 33620
PTM EXONT:000340 N6-glycyl-L-lysine 14 33618 33620
PTM EXONT:000164 O4'-phospho-L-tyrosine 14 33660 33662
PTM EXONT:000161 O-phospho-L-serine 14 33669 33671
PTM EXONT:000161 O-phospho-L-serine 14 33693 33695
PTM EXONT:000162 O-phospho-L-threonine 15 36082 36084
PTM EXONT:000797 Ubiquitinylated lysine 15 36085 36087
PTM EXONT:000162 O-phospho-L-threonine 15 36196 36198
PTM EXONT:000161 O-phospho-L-serine 15 36205 36210
PTM EXONT:000164 O4'-phospho-L-tyrosine 16 37186 37188
PTM EXONT:000180 N-acetylated L-lysine 17 39955 39957
PTM EXONT:000192 N6-acetyl-L-lysine 17 39955 39957
Unclassified EXONT:007612 Zinc finger, Mcm10/DnaG-type 9,10 24653 27390
Unclassified EXONT:007615 Replication factor Mcm10 12,13,14,15,16,17,18,19,20 30749 47748
Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10
Gene MCM10 Gene MCM10

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Exon 16Exon 17Exon 18Exon 19Exon 20Extended region