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Previous gene FasterDB identifier: 13788 - A1CF (ACF, ACF64, ACF65, APOBEC1CF, ASP) APOBEC1 complementation factor Next gene
Gene Close
Symbol A1CF
Synonyms ACF, ACF64, ACF65, APOBEC1CF, ASP
Description APOBEC1 complementation factor
EnsEMBL link ENSG00000148584
Chromosome 10 - reverse strand
Chromosomal location
(UCSC link)
52559169 - 52645436 (86268bp)
Sequence sequence
Associated transcripts AK000324 BC054873 NM_014576 NM_138933 NM_001198818 NM_001198819 NM_001198820 NM_138932 AK303801 AF209192 AK291982 BC130519 BC144196 BC144194 AJ272078 AJ272079 AF271789 AF271790
Alternative 3' splice site (acceptor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 12 24 AK000324
NM_014576
NM_138933
NM_001198818
NM_001198820
AF209192
AK291982
BC144196
BC144194
AJ272079
AF271789
AF271790
Alternative 5' splice sites (donor) Close
 Identifier   Position   Distance (bp)   Transcript 
ASS1 5 -11 AK000324
NM_138933
NM_001198819
NM_001198820
AK303801
BC144196
Intron retentions Close
 Identifier   Position   Transcript 
Exon deletions Close
 Identifier   Position   Transcript 
No data
Transcription start sites Close
 Identifier   Position   Gene coordinates   Chromosomal coordinates   Transcript 
P1 1 1 52645436 AK000324
BC054873
P2 1 48 52645389 AK303801
P3 1 50 52645387 AK291982
Protein prediction Close
 Transcript name   Sequence 
AK000324 sequence
BC054873 sequence
NM_014576 sequence
NM_138933 sequence
NM_001198818 sequence
NM_001198819 sequence
NM_001198820 sequence
NM_138932 sequence
AK303801 sequence
AF209192 sequence
AK291982 sequence
BC130519 sequence
BC144196 sequence
BC144194 sequence
AJ272078 sequence
AJ272079 sequence
AF271789 sequence
AF271790 sequence
Polyadenylation Close
 Identifier   Position   Gene coordinates of cleavage site   Chromosomal coordinates of cleavage site   Pattern   PolyA tail   Accession number   Type 
PA1 7 43853 52601584 ATTAAA yes BC054873 Cdna
PA2 15 79017 52566420 ATTAAA no AK303801 Full_length
PA3 15 79130 52566307 no AK291982 Full_length
PA4 15 85645 52559792 AATAAA no AI022398 3prime_est
PA5 15 85645 52559792 AATAAA no AI032955 3prime_est
PA6 15 86268 52559169 TATAAA no NM_014576 Cdna
PA7 15 86268 52559169 TATAAA no NM_138933 Cdna
PA8 15 86268 52559169 TATAAA no NM_001198818 Cdna
PA9 15 86268 52559169 TATAAA no NM_001198819 Cdna
PA10 15 86268 52559169 TATAAA no NM_001198820 Cdna
PA11 15 86268 52559169 TATAAA no NM_138932 Cdna

More polyadenylation sites ...

Exon skipping Close
 Identifier   Position   Transcript 
ES1 2 AK000324
BC054873
NM_138933
ES2 3 AK000324
BC054873
NM_014576
NM_138933
NM_001198820
NM_138932
AF209192
BC130519
BC144196
ES3 5 BC054873
NM_014576
NM_001198818
NM_138932
AF209192
AK291982
BC130519
BC144194
AJ272078
AJ272079
AF271789
Splice site strength Close
 Identifier   Site   Exon   Strength   Alternative   Sequence 
S1 5' (donor) 1 9.46 no CAGgtatga
S2 5' (donor) 2 6.69 no TATgtaagt
S3 3' (acceptor) 2 7.15 no tctcacccatcctcaactagATA
S4 5' (donor) 3 -1.06 no GAGgtgtaa
S5 3' (acceptor) 3 5.41 no atataaacttgtcatttcagCAT
S6 5' (donor) 4 9.79 no CAGgtagga
S7 3' (acceptor) 4 6.36 no tatcttaaatttggtttcagTGA
S8 5' (donor) 5 -6.15 no AGGgtctta
S9 3' (acceptor) 5 3.81 no acctaattacttcttgaaagGAA
S10 5' (donor) 5 10.22 yes AAGgtaagc
S11 5' (donor) 6 8.4 no AAAgtgagt
S12 3' (acceptor) 6 7.95 no cacctgccctggatttgcagGAA
S13 5' (donor) 7 8.89 no TAGgtaagc
S14 3' (acceptor) 7 9.52 no tctatttctattacttgcagATC
S15 5' (donor) 8 4.9 no CAGgttagc
S16 3' (acceptor) 8 10.14 no aatccctgctctttttgcagAAA
S17 5' (donor) 9 9.79 no CAGgtagga
S18 3' (acceptor) 9 7.59 no atggtgatcattttcaacagGAA
S19 5' (donor) 10 10.51 no AAGgtaagg
S20 3' (acceptor) 10 11.08 no accttcactctattttacagGTG
S21 5' (donor) 11 8.1 no GAGgtaaca
S22 3' (acceptor) 11 10.5 no ttctttgctctctacaacagGTG
S23 5' (donor) 12 10.28 no CAGgtaggt
S24 3' (acceptor) 12 8.45 no atgccttcttacgttcctagAAA
S25 3' (acceptor) 12 5.95 yes ttacatgaatgtacctgtagGGG
S26 5' (donor) 13 5.02 no AATgtgcgt
S27 3' (acceptor) 13 8.41 no aactttttttattcttgtagATA
S28 5' (donor) 14 9.99 no CAGgtatgg
S29 3' (acceptor) 14 7.23 no ctgactgacttgctttccagCCA
S30 3' (acceptor) 15 12.66 no ttctctgcctcttcctccagGAT
Conserved exons Close
 Gene identifier mouse   Position human  Position mouse 
1985 1 1
1985 4 2
1985 6 3
1985 7 4
1985 8 5
1985 9 6
1985 10 7
1985 11 8
1985 12 9
1985 13 10
1985 14 11
Report Close
 Exon   Number of supporting transcripts 
 Transcription initiation & first exon(s) 
1 3
 Transcription termination & last exon(s) 
7 1
15 10
 Exon skipping 
2 3
3 9
5 11
 Alternative 3' splice sites 
12 1
 Alternative 5' splice sites 
5 1
Splicing factors Close
 Splicing factor   Exon array   CLIP data   Exon position 
CELF1 (CUG-BP)
 
DAZAP1
 
ELAVL1 (HuR) Yes Yes
 
ESRP1/2 (ESRP) Yes
 
FUS Yes
 
HNRNPA1 Yes
 
HNRNPA2B1 Yes
 
HNRNPAB
 
HNRNPC Yes
 
HNRNPF/HNRNPH1 Yes Yes
 
HNRNPL Yes
 
HNRNPL_2
 
HNRNPM Yes
 
HNRNPU Yes
 
MBNL
 
NOVA1
 
PTBP1/2 (PTB) Yes Yes
 
QKI
 
RBFOX2 (FOX2) Yes
 
RBM4 Yes
 
SFRS3 (SRP20)
 
SFRS6 (SRP55)
 
SFRS7 (9G8)
 
SRSF1 (SF2ASF)
 
SRSF2 (SC35)
 
SRSF5 (SRP40)
 
TDP43
 
TIA1/TIAL1 Yes
 
TRA2A
 
TRA2B
 
YBX1 (YB1)
 
Expression Close
 Exon position   Tissues   Cell lines   Cancer cell lines 
1 Expression Expression Expression
2 Expression Expression Expression
3 Expression Expression Expression
4 Expression Expression Expression
5 Expression Expression Expression
6 Expression Expression Expression
7 Expression Expression Expression
8 Expression Expression Expression
9 Expression Expression Expression
10 Expression Expression Expression
11 Expression Expression Expression
12 Expression Expression Expression
13 Expression Expression Expression
14 Expression Expression Expression
15 Expression Expression Expression
Exon-Intron Close
 Position   Type   Gene coordinates   Chromosomal coordinates   Length   Sequence   Features 
1 Exon 1 - 96 52645341-52645436 96 sequence download
1 Intron 97 - 21596 52623841-52645340 21500 sequence -
2 Exon 21597 - 21644 52623793-52623840 48 sequence download
2 Intron 21645 - 22695 52622742-52623792 1051 sequence -
3 Exon 22696 - 22788 52622649-52622741 93 sequence download
3 Intron 22789 - 25691 52619746-52622648 2903 sequence -
4 Exon 25692 - 25835 52619602-52619745 144 sequence download
4 Intron 25836 - 34869 52610568-52619601 9034 sequence -
5 Exon 34870 - 35023 52610414-52610567 154 sequence download
5 Intron 35024 - 41554 52603883-52610413 6531 sequence -
6 Exon 41555 - 41689 52603748-52603882 135 sequence download
6 Intron 41690 - 43684 52601753-52603747 1995 sequence -
7 Exon 43685 - 43815 52601622-52601752 131 sequence download
7 Intron 43816 - 49364 52596073-52601621 5549 sequence -
8 Exon 49365 - 49603 52595834-52596072 239 sequence download
8 Intron 49604 - 57381 52588056-52595833 7778 sequence -
9 Exon 57382 - 57546 52587891-52588055 165 sequence download
9 Intron 57547 - 65027 52580410-52587890 7481 sequence -
10 Exon 65028 - 65125 52580312-52580409 98 sequence download
10 Intron 65126 - 69397 52576040-52580311 4272 sequence -
11 Exon 69398 - 69671 52575766-52576039 274 sequence download
11 Intron 69672 - 71614 52573823-52575765 1943 sequence -
12 Exon 71615 - 71820 52573617-52573822 206 sequence download
12 Intron 71821 - 74500 52570937-52573616 2680 sequence -
13 Exon 74501 - 74637 52570800-52570936 137 sequence download
13 Intron 74638 - 75634 52569803-52570799 997 sequence -
14 Exon 75635 - 75783 52569654-52569802 149 sequence download
14 Intron 75784 - 78796 52566641-52569653 3013 sequence -
15 Exon 78797 - 86268 52559169-52566640 7472 sequence download
Close  5' untranslated regions 
 UTR 1   UTR 2   UTR 3   UTR 4   UTR 5   UTR 6   UTR 7 
 Supporting GenBank
accession identifers 
AK291982
BC054873
NM_001198819
NM_001198818
NM_001198820
BC144196
NM_014576
NM_138932
AF209192
BC130519
AK303801
AK000324
NM_138933
AF271790
BC144194
 Length  233 140 400 307 399 747 671
 Number of ATGs in frame  0 0 0 0 0 12 14
 Total number of ATGs  3 1 6 3 6 22 21
 Number of GTGs in frame  2 1 2 1 3 6 6
 Total number of GTGs  7 3 8 6 9 12 13
 Number of CTGs in frame  3 2 2 1 3 7 6
 Total number of CTGs  5 3 6 5 6 10 10
 Number of micro ORFs in frame  0 0 0 0 0 2 1
 Total number of micro ORFs  1 1 3 2 2 4 2
 GC percentage  38 43 43 44 45 43 41
 Number of pyrimidine tracks  2 0 2 1 2 1 3
Close 3' untranslated regions 
 UTR 1   UTR 2 
 Supporting GenBank
accession identifers 
BC054873
NM_014576
NM_138933
NM_001198818
NM_001198819
NM_001198820
NM_138932
AK291982
BC144196
BC144194
BC130519
AK303801
AK000324
AF209192
 Length  35 7320
 Number of ATGs in frame  0 37
 Total number of ATGs  0 121
 Number of GTGs in frame  0 31
 Total number of GTGs  0 104
 Number of CTGs in frame  0 19
 Total number of CTGs  1 52
 GC percentage  43 34
 Number of pyrimidine tracks  1 53
miRNAs Close
 Identifier    Name    Gene coordinates   Chromosomal coordinates   Prediction algorithm 
Group 1
M1 hsa-miR-494 79032 - 79053 52566384 - 52566405 miranda
M2 hsa-miR-433 79087 - 79108 52566329 - 52566350 miranda
Protein features Close
 Category   Feature identifier   Feature name   Exons   Start on gene   End on gene 
Binding EXONT:001885 Protein binding 4,6,7,8 25737 49365
Binding EXONT:002265 RNA recognition motif domain 6,7,8 41621 49401
Binding EXONT:006334 Nucleotide-binding, alpha-beta plait 6,7,8,9,10,11 41630 69487
Binding EXONT:002265 RNA recognition motif domain 8,9 49405 57431
Binding EXONT:002265 RNA recognition motif domain 9,10,11 57468 69439
Localization EXONT:000064 Nuclear_localization_signal 5 35008 35019
Localization EXONT:000067 Nuclear_export_signal 6,7 41684 43720
Localization EXONT:000064 Nuclear_localization_signal 10 65045 65056
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 4 25737 25790
Structure EXONT:000074 Intrinsically_unstructured_polypeptide_region 6 41555 41605
Structure EXONT:000051 Beta_strand 9 57471 57488
Structure EXONT:000037 Peptide_helix 9 57507 57533
Structure EXONT:000051 Beta_strand 10 65033 65050
Structure EXONT:000051 Beta_strand 10 65054 65083
Structure EXONT:000037 Peptide_helix 10 65084 65116
Structure EXONT:000051 Beta_strand 10,11 65117 69403
Structure EXONT:000051 Beta_strand 11 69410 69427
PTM EXONT:000164 O4'-phospho-L-tyrosine 8 49555 49557
PTM EXONT:000162 O-phospho-L-threonine 11 69467 69469
PTM EXONT:000164 O4'-phospho-L-tyrosine 12 71674 71676
PTM EXONT:000164 O4'-phospho-L-tyrosine 12 71683 71685
PTM EXONT:000164 O4'-phospho-L-tyrosine 12 71704 71706
PTM EXONT:000164 O4'-phospho-L-tyrosine 12 71740 71742
PTM EXONT:000162 O-phospho-L-threonine 14 75645 75647
PTM EXONT:000161 O-phospho-L-serine 14 75660 75662
PTM EXONT:000162 O-phospho-L-threonine 14 75684 75686
PTM EXONT:000164 O4'-phospho-L-tyrosine 15 78799 78801
PTM EXONT:000162 O-phospho-L-threonine 15 78817 78819
Unclassified EXONT:006962 Double-stranded RNA-binding domain 13 74501 74611
Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF
Gene A1CF Gene A1CF

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Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 1Exon 2Exon 3Exon 4Exon 5Exon 6Exon 7Exon 8Exon 9Exon 10Exon 11Exon 12Exon 13Exon 14Exon 15Extended region